Department of Medical Imaging, Clinical Hospital of Medical College, Nanjing University, Nanjing Military General Hospital of PLA, Nanjing 210002, China
Abstract：Objective: To determine the effect of computer aided detection(CAD) system on the diagnosis of pulmonary nodules. Methods: One hundred and fifty cases with solitary lung nodules up to 9~30mm in diameter were examined. All nodules had been verified by means of biopsy. One hundred and fifty cases of healthy individuals were selected as control group on the basis of chest CT. All chest radiographs in the two groups were obtained with a digital radiography system. Five experienced chest radiologists and five residents detected the chest radiograph with or without CAD output images. The scales of performance was evaluated with receiver operating characteristic analysis. Result: The average area under the curve value increased significantly from 0.766 without CAD to 0.833 with CAD output images. Individually, the use of CAD output images was more useful to radiology residents than to experienced radiologist. Conclusion: This CAD system for digital radiograph can assist radiologist and has the potential to improve the detection of lung nodules.
2006, Vol. 17 
