Study of diffusion tensor imaging in necrotic brain tumors and abscess
SHI Rui-hua1, QI Ming-chen2, ZHAI Ren-you1, QIAN Xiao-jun1, LU Wan-hong1, GU Hua1
1.Department of Radiology, Chaoyang Hospital, Capital University of Medical Sciences, Beijing 100020, China;2.Shandong Provincial Chest Hospital, Jinan 250013, China
Abstract：Objectives: To evaluate the diagnostic value of diffusion tensor imaging(DTI) in brain tumors with necrosis and abscesses. Materials and Methods?押 Nine brain abscesses, 12 glioblastomas, 10 metastases confirmed clinically or pathologically underwent conventional MRI and DTI. Average diffusion coefficient(ADC) value, fractional anisotropy(FA) value and map was calculated in the central portion. Results: On DTI, The abscesses displayed as hyperintense signal; but glioblastoma and metastasis all showed hypointense signal. On ADC map, the abscesses showed hypointense signal, the mean ADC value was (0.66±0.07)×10-3mm2/s, The difference between abscess and necrotic tumors was statistically significant(P=0.000<0.05); glioblastoma and metastasis all demonstrated as hyperintense signal. Abscess, glioblastoma, metastases and peri-edema all were depicted as hypointense signal on FA map. Conclusion: Abscesses show special hyperintense signal on DTI and have low ADC value. DTI is helpful in differentiating abscess from glioblastoma and metastasis.
2006, Vol. 17 
