Abstract：Objective: To evaluate the value of 99mTc-MDP SPECT/CT fusion imaging in differentiating malignant from benign single spinal radioactive‘hot spot’ abnormality. Methods: There were 131 patients underwent bone scan and SPECT/CT tomography. The diagnosis was made by two doctors from Nuclear Medicine Department. Results: Of the 131 lesions detected in whole body scan, 34(26.0%) were malignant lesions and 94(71.7%) were benign lesions, 3(2.3％) were primary bone tumors. SPECT/CT fusion imaging can supply the precise anatomical location of the conventional bone scan abnormalities. And show the associated location and shape in benign and malignant spinal lesions. It can significantly reduce the false-positive rate of bone scan in diagnosis of bone metastases; diagnosis of types of bone metastases as well. Conclusion: SPECT/CT fusion imaging has significant clinical value in differentiating malignant from benign single spinal radioactive ‘hot spot’ abnormality.
2010, Vol. 21 
