Relation of vascular performance of MRI-DCE and tumor shape, partial biological characteristics of breast cancer
DONG Yong-xing1, SUN Peng-fei2, ZHANG Yong-hai1, SUN Yan-qiu1
1. Department of Radiology, People’s Hospital of Qinghai Province, Xining 810700, China;
2. Department of Radiotherapy, the Second Hospital of Lanzhou University, Lanzhou 730030, China
Abstract:Objective: To discuss the relation between the vascular scores of invasive ductal carcinoma(IDC) on MRI-DCE with mass type, lymph node metastasis and ER, PR expression of breast cancer. Methods: All of 28 cases(35 lesions) with breast cancer underwent 3.0T MRI dynamic contrast-enhanced scan, the vascular images of 3D maximum intensity projection were got and the scores of the adjacent blood vessels were estimated. The correlation of vessels scores with tumor morphology(mass type and no-mass type), lymph node metastasis and ER, PR were analyzed. Result: There were higher vessels scores in no-mass type group than mass type(P<0.05), the lymph node metastasis group was higher than no metastasis(P<0.05), the ER positive group was lower than ER negative(P<0.01). Conclusion: The vascular performances of adjacent breast cancer lesions on MRI-DCE are related to mass type and lymph node metastasis, ER expression. It is useful to predicate the biological characteristics and value curative effect of breast cancer.
董永兴1,孙鹏飞2,张永海1,孙艳秋1. MR动态增强血管评分与乳腺癌形态及#br#
部分生物学行为间的相关性探讨[J]. 中国临床医学影像杂志, 2016, 27(11): 778-780.
DONG Yong-xing1, SUN Peng-fei2, ZHANG Yong-hai1, SUN Yan-qiu1. Relation of vascular performance of MRI-DCE and tumor shape, partial biological characteristics of breast cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(11): 778-780.
[1]Parker GJ, Sucklling J, Tanner SF, et al. Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics[J]. J Magn Reson Imaging, 1997, 23(7): 564-574.
[2]Passe TJ, Bluemke DA, Siegelman SS. Tumor angiogenesis: tutorial on implications for imaging(Review)[J]. Radiology, 1997, 203(17): 593-600.
[3]Schmitz AC, Peters NH, Veldhuis WB. Contrast-enhanced 3.0-T breast MRI for characterization of breast lesions: increased specificity by using vascular maps[J]. Eur Radiol, 2007, 18(2): 355-364.
[4]Mahfouz AE, Sherif H, Saad A, et al. Gadolinium-enhanced MR angiography of the breast cancer associated with ipsilateral higher vascularity?[J]. Eur Radiol, 2001, 11(6): 965-969.
[5]Choi Y, Chang Y, Park H, et al. Correlation of the apparent diffusion coefficiency values on diffusion-weighted imaging with prognostic factors for breast cancer[J]. Br Radiol, 2012, 85(11): e474-e479.
[6]Kim SH, Cha ES, Kin HS, et al. Diffusion-weighted imaging of breast cancer: correlation of the apparent diffusion coefficient value with prognostic factors[J]. J Magn Reson Imaging, 2009, 30(9): 615-620.
[7]Sardanelli F. Vascular maps on contrast-enhanced breast MR images: a new approach requiring further investigation[J]. Radiology, 2008, 247(1): 295-296.
[8]芦艳,张文慧. 瘤内动脉入射角度和瘤周动脉管径的改变对乳腺癌诊断的价值研究[J]. 实用癌症杂志,2014,29(10):1248-1252.
[9]彭程宇,刘万花,王瑞,等. 探讨乳腺癌MR动态增强图像的血管表现与肿瘤形态、大小及病理分级的相关性[J]. 中国医学影像技术,2012,28(10):1848-1851.
[10]黄伟,曹建民,陈自谦,等. 乳腺癌肿瘤血管的影像学研究及其与肿瘤分期的关系[J]. 临床放射学杂志,2004,23(1):41-44.
[11]李彭,汤光宇,刘勇,等. 乳腺癌MR动态增强与预后因子的相关性研究[J]. 临床放射性杂志,2008,27(8):1042-1044.
[12]Laura M, Veronica D, Ilaria B, et al. Correlations between diffusion-weighted imaging and breast cancer biomarkers[J]. Eur Soc Radiol, 2012, 22(6): 1519-1528.
[13]王黎明. 乳腺浸润性导管癌3T磁共振动态增强特征与预后的相关性研究[J]. 中国医学影像学杂志,2011,19(8): 596-600.
[14]Jeh SK, Kim SH, Kim HS, et al. Correlation of the apparent diffusion coefficient value and dynamic magnetic resonance imaging findings with prognostic factors in invasive ductal carcinoma[J]. Magn Reson Imaging, 2011, 33(1): 102-109.