Abstract：Objective: To explore the clinical value of transvaginal real-time three-dimensional hysterosalpingo contrast sonography(RT-3D-HyCoSy) in the assessment of tubal patency. Methods: Imaging data of 62 patients with infertility examined by transvaginal RT-3D-HyCoSy was analyzed retrospectively, in which 25 cases were compared with laparoscopic hydrotubation. Results: One hundred and twenty one fallopian tubes were showed by RT-3D-HyCoSy in the 62 patients(3 patients had unilateral tube), among which 54 tubes were diagnosed to be patency, 41 incompletely occluded, and 26 occluded. RT-3D-HyCoSy was compared with laparoscopic hydrotubation in 25 cases, with the total coincidence rate of 86.00%(43/50) and consistency checking Kappa value of 0.702(P>0.05), showing high consistency for the two methods. Conclusion: RT-3D-HyCoSy could dynamically display the morphological character of fallopian tube real-time. RT-3D-HyCoSy is an accurate and effective approach to assess fallopian tube patency.
[1]Ahinko-Hakamaa K, Huhtala H, Tinkanen H. The validity of air and saline hysterosalpingo-contrast sonography in vubal patency investigation before insemination treatment[J]. Obstet Gynecol Reprod Biol, 2007, 132(1): 83-87.
[2]张艳玲，张新玲，郑荣琴，等. 经阴道子宫输卵管三维超声造影评价输卵管的通畅性[J]. 中华超声影像学杂志，2011，20（4）：318-320.
[3]Savelli L, Pollastri P, Guerrini M, et al. Tolerability, side effects, and complications of hysterosalpingocontrast sonography(HyCoSy)[J]． Fertil Steril, 2009, 92(4): 1481-1486.
[4]廖建梅，杨舒萍，林彦銮，等. 经阴道实时三维超声子宫输卵管造影与腹腔镜检查评价输卵管通畅性[J]. 中国超声医学杂志，2015，31（12）：1117-1119.
[5]Exacoustos C, Di Giovanni A, Szabolcs B, et al. Automated three-dimensional coded contrast imaging hysterosalpingo-contrast sonography: feasibility in office tubal patency testing[J]. UItrasound Obstet Gynecol, 2013, 41(3): 328-335.
[6]Lanzani C, Savasi V, Leone FP, et al. Two-dimensional HyCoSy with contrast tuned imaging technology and a second-generation contrast media for the assessment of tubal patency in an infertility program[J]. Fertil Steril, 2009, 92(3): 1158-1161.
[7]韩丽萍，李一冬，刘芳. 子宫输卵管造影致肺栓塞40例临床分析[J]. 实用妇产科杂志，2001，17（4）：240-241.
[8]张迎，程琦，王泓，等． 经阴道二维超声和三维子宫输卵管超声造影评价输卵管通畅性的对比研究[J]. 临床超声医学杂志，2012，14（7）：440-443.
[9]Socolov D, Boian I, Boiculese L, et al． Comparison of the pain experienced by infertile women undergoing hysterosalpingo contrast sonography or radiographic hysterosalpingography[J]. Int J Gynaecol Obstet, 2010, 111(3): 256-259．
[10]李辉，陈芸，薛敏，等． 经阴道实时三维超声输卵管造影与X线碘油输卵管造影的比较研究[J]． 中国超声医学杂志，2014，30（10）：923-926.
[11]张新玲，郑荣琴，黄冬梅，等． 双氧水声学造影评价输卵管的通畅性[J]． 中国超声诊断杂志，2004，7（4）：271－273.
[12]骆玉妓，古丽娜尔·沙海，向红，等. 经阴道三维超声造影评价输卵管的通畅性[J]. 中国医学影像技术，2013，29（1）：97-99.
[13]Nirmal D, Uriffiths AN, Jose G, et al. Warming Echovist contrast medium for hysterocontrastsonography and the effect on the incidence of pelvic pain. A randomized controlled study[J]. Hum Reprod, 2006, 21(4): 1052-1054.
