Morphometric study of MR sequence in the cisternal segment of trigeminal nerve in patients with trigeminal neuralgia
HE Yun-yun1, QI Xi-xun1, ZHANG Su-ya1, REN Si-xie1, SHI Da-fa2, GUAN Li-ming1
1. Department of Radiology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;
2. Department of Radiology, the First People’s Hospital of Jingzhou, Jingzhou Hubei 434000, China
Abstract：Objective: To investigate the changes of morphological structures in trigeminal neuralgia(TN) affected trigeminal nerve by using MR to measure the morphology of the cisternal segment of the trigeminal nerve in TN patients and the control group． Methods: Forty-five TN patients and forty-five healthy volunteers were enrolled in this study and scanned by GE 3.0T high resolution MR． Three dimensional time of flight spoiled gradient recalled acquisition(3D-TOF-SPGR) and three dimensional fast imaging employing steady state acquisition(3D-FIESTA) were used to measure morphological structures in cisternal segment of bilateral trigeminal nerve. All images were done postprocessing by reformat software. The length of the cisternal segments of the trigeminal nerve, the maximum cross-sectional areas of the nerves in coronal, axial and sagittal image, the trigeminal-pontine angle, the turn angles of the nerves passing the petrosal bones, and the distance of the neurovascular compression were measured. Then compared and analyzed the measurements and drew the ROC curve by the different ratios of the morphological measurements in the sequence of SPGR and FIESTA between bilateral trigeminal nerve of TN patients and control group. Values with P<0.05 were considered statistically significant. Results: The length of the cisternal segments of the trigeminal nerve, the maximum cross-sectional areas of the nerves in coronal, axial and sagittal image on the symptomatic side were smaller than that on the asymptomatic side and the control group(P<0.05), but the bilateral trigeminal-pontine angle and the turn angles of the nerves passing the petrosal bones had no difference both in patients and the control group(P>0.05). The length of the cisternal segments trigeminal nerve, the maximum cross-sectional areas of the nerves in coronal, axial and sagittal image on the control group were greater than that on the asymptomatic side(P<0.05), the bilateral trigeminal-pontine angle and the turn angles of the nerves passing the petrosal bones in the control group had no difference with the asymptomatic side. In the different ratios of the morphological measurements in these sequence, the different ratios of the maximum cross-sectional areas of the nerves in the coronal of the SPGR sequence had the best diagnosis efficiency. 84.4% of the neurovascular compression point in TN patient was near the nerve root, the mean distance of the neurovascular compression point was (2.124±1.478) mm. Conclusion: Morphometric measurement of MR sequence in the cisternal segment of trigeminal nerve can display the morphology change of trigeminal nerve more intuitively, increase the objectivity of the clinical TN diagnosis and provides a new method and sight for the diagnosis of TN.
贺芸芸1，戚喜勋1，张苏雅1，任思勰1，石大发2，关丽明1. 三叉神经痛患者三叉神经脑池段MR形态测量研究[J]. 中国临床医学影像杂志, 2017, 28(4): 233-239.
HE Yun-yun1, QI Xi-xun1, ZHANG Su-ya1, REN Si-xie1, SHI Da-fa2, GUAN Li-ming1. Morphometric study of MR sequence in the cisternal segment of trigeminal nerve in patients with trigeminal neuralgia. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(4): 233-239.
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