Abstract：Objective: To evaluate the value of quantitative parameters of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant lung lesions. Methods: Fifty-one cases of lung lesions diagnosed by puncture pathology were divided into benign group and malignant group, the quantitative parameters of contrast-enhanced ultrasonography time intensity curve(TIC) and the time difference of contrast agent to lung lesions and adjacent lung tissues were quantitatively analyzed. Results: ①In the quantitative parameters of TIC, the contrast agent arrive time(AT) in the benign group was less than that in the malignant group, and the difference was statistically significant between the two groups(P<0.05). There was no significant difference in the time to peak(TTP), the rise time(RT), the maximum intensity(IMAX) and the rising slope(RS) between the two groups(P>0.05). ②Squamous cell carcinoma group and adenocarcinoma group were divided from malignant group. There was no significant difference in quantitative parameters of TIC between the two groups(P>0.05). ③The time difference of contrast agent to lung lesions and adjacent lung tissues in the benign group was less than that in the malignant group, and the difference was statistically significant between the two groups(P<0.05). The optimal cut-off point of the time difference was 2.5 s. Conclusion: ①The quantitative parameters of TIC have definite clinical value in the differential diagnosis of benign and malignant lung lesions. ②The time difference of contrast agent to lung lesions and adjacent lung tissues has certain value in the differential diagnosis of benign and malignant lung lesions. The time difference<2.5 s indicates that the lesions tend to be benign, and the time difference>2.5 s indicates that the lesions tend to be malignant.
朱丽静，王兴华. 超声造影定量参数对肺部良恶性病变鉴别诊断的研究[J]. 中国临床医学影像杂志, 2020, 31(1): 34-37.
ZHU Li-jing, WANG Xing-hua. Study on differential diagnosis of benign and malignant lung lesions with quantitative parameters of#br#
contrast-enhanced ultrasonography. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(1): 34-37.
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