Abstract：Objective: To investigate the application value of first trimester fetal echocardiography in the prenatal diagnosis of severe congenital heart disease(CHD). Methods: First trimester fetal echocardiography was performed in 1 209 fetuses. Four-chamber view, three vessels and trachea view, left ventricular outflow tract view, right ventricular outflow tract view and aortic arch view were obtained. Patients with suspected cardiac abnormalities were reexamined for fetal echocardiography after 2-4 weeks. Pathological examination is required for induced labor after diagnosis. Fetal echocardiography was performed at 18-24 weeks for those who continue pregnancy. All live births were followed up by echocardiography. Results: Thirteen fetuses with severe congenital heart disease were diagnosed by first trimester fetal echocardiography, including 7 cases of conotruncal anomalies, 3 cases of hypoplastic left heart syndrome, 2 cases of atrioventricular septal defect and 1 case of Ebstein’s anomaly. 16 cases were confirmed in mid-pregnancy and post-natal follow-up, one case was missed and 4 cases were misdiagnosed. The diagnostic accordance rate was 68.7%(11/16). Conclusions: Most CHDs could be diagnosed by first trimester fetal echocardiography, especially those with abnormal four chambers views. Echocardiography in early pregnancy has important application value in the diagnosis of severe congenital heart disease.
张 俊，邓学东，潘 琦，殷林亮，马建芳，杨 忠，苟中山. 早孕期超声心动图在胎儿严重先心病中的应用[J]. 中国临床医学影像杂志, 2019, 30(1): 28-31.
ZHANG Jun, Deng Xu-dong, PAN Qi, YIN Lin-liang, MA Jian-fang, YANG Zhong, GOU Zhong-shan. The application of echocardiography in diagnosing fetal severe congenital heart disease at first trimester. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(1): 28-31.
2019, Vol. 30 
