Abstract：Objective: To summarize the high-frequence ultrasound features in peripheral neuropathy(DPN) patients of type 2 diabetes, and to analyze their correlation with neural eletrophysiological examination. Methods: According to neural eletrophysiological examination, forty patients with type 2 diabetes mellitus were divided into the non-DPN group(group A, 20 cases) and DPN group (group B, 20 cases), and 23 non-diabetic patients were enrolled as the control group(group C). The diameter(D1), anteroposterior diameter(D2) and cross-sectional area(CSA) were measured in seven points of median nerve. Then, the ultrasound imaging features were observed. Moreover, the correlation between ultrasound and neural eletrophysiological examination was analyzed. Results: Sixty-three participants(36 men, 27 women, average age (54.32±12.08) years old) were enrolled. ①Compared with group C, D1, D2 and CSA of group A and B were often increased with significant difference. Compared with group A, D1 and CSA of group B were often increased with significant difference.②On the basis of the receiver operating characteristic curve, the highest diagnosis value was at MN6 level, and the cutoff values of CSA were 9.61 mm2 and 10.65 mm2. ③Moreover, the disappearance of screen structure, hypoechoic, thickened epineurium and increased blood flow was shown, especially at the level of MN4, MN5, MN6. ④According to correlation analysis, CSA was positively correlated with distal motor latency and negatively correlated with motor conduction velocity, sensory conduction velocity and sensory nerve action potential amplitude. Conclusion: DPN represents with the increase of D1, D2 and CSA, the disappearance of screen structure, hypoechoic, thickened epineurium and increased blood flow. Moreover, there is some correlation between ultrasound and neural eletrophysiological examination. To some extent, high-frequence ultrasound could help diagnose DPN early.
马西顺，杜丽珍，类婷婷，韩彤亮. 2型糖尿病周围神经病变高频超声及电生理学特征分析[J]. 中国临床医学影像杂志, 2019, 30(10): 734-737.
MA Xi-shun, DU Li-zhen, LEI Ting-ting, HAN Tong-liang. Feature analysis of high-frequence ultrasound and neural eletrophysiological examination in peripheral neuropathy caused by type 2 diabetes mellitus. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(10): 734-737.
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