膝关节骨关节炎半月板损伤程度与关节软骨
T1 rho、T2 mapping相关性研究

doi:10.12117/jccmi.2019.11.012

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摘要目的：探讨膝关节骨关节炎（OA）患者关节软骨T1 rho、T2值与半月板损伤分级之间的关系。方法：选择膝关节OA患者80例。应用3.0T MRI设备（GE MR 750）扫描膝关节常规序列及T1 rho、T2 mapping序列，对半月板后角损伤程度分级，并测量对应区域关节软骨T1 rho、T2值。结果：半月板损伤程度越高，邻近关节软骨T1 rho、T2值越高，不同半月板分级之间关节软骨T1 rho、T2弛豫时间有差异，其差异显著、具有统计学意义（P<0.05）。结论：膝关节半月板损伤程度越重，关节软骨损伤越严重，在关节软骨形态学改变之前，可以根据半月板损伤情况评估关节软骨损伤情况，对临床上早期膝关节OA患者干预治疗有重要的临床意义。

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	赵敏
	刘鸿雁
	王国华
	张炳
	高健
	赵鸿飞

关键词 ：膝关节, 骨关节炎, 磁共振成像

Abstract：Objective: To investigate the relationship between T1 rho and T2 values of articular cartilage and meniscus injury grading in patients with knee osteoarthritis(OA). Methods: Eighty patients with knee OA were selected. The 3.0T MRI(GE 750 Discovery) was used to scan the conventional knee sequence and the T1 rho and T2 mapping sequences. The degree of meniscus injury was graded and the T1 rho and T2 values of articular cartilage were measured. Results: With the improvement of meniscus grading, the T1 rho and T2 value of adjacent articular cartilage increased. The T1 rho and T2 relaxation time of articular cartilage differed significantly between different meniscus grading(P<0.05). Conclusion: Before the morphological changes of articular cartilage, the damage of articular cartilage can be evaluated according to the meniscus injury, which has important clinical significance for the intervention of early OA patients.

Key words： Knee joint Osteoarthritis Magnetic resonance imaging

收稿日期: 2019-01-16

PACS:	Ｒ684.3
	Ｒ445.2

通讯作者: 王国华，青岛大学附属青岛市市立医院放射科，266011。E-mail：wangguohua89@163.com

作者简介: 赵敏（1989-），女，山东枣庄人，住院医师。E-mail：cilinzaw@163.com

引用本文:

赵敏，刘鸿雁，王国华，张炳，高健，赵鸿飞. 膝关节骨关节炎半月板损伤程度与关节软骨 T1 rho、T2 mapping相关性研究[J]. 中国临床医学影像杂志, 2019, 30(11): 812-816.
ZHAO Min, LIU Hong-yan, WANG Guo-hua, ZHANG Bing, GAO Jian, ZHAO Hong-fei. The correlation between the degree of meniscus injury of knee osteoarthritis and T1 rho, T2 mapping of the articular cartilage. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(11): 812-816.

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http://www.jccmi.com.cn/CN/10.12117/jccmi.2019.11.012 或 http://www.jccmi.com.cn/CN/Y2019/V30/I11/812

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