Abstract：Objective: To explore CT features of large cell lung carcinoma(LCLC). Methods: CT findings in 15 cases of LCLC confirmed by surgery and pathology were retrospectively analyzed. Imaging were obtained by whole body CT in 10 cases and multi-slice spiral CT(MSCT) in the others. Results: The lesions were all presented as peripheral. Most of them were located in peripheral areas with a mean size of 4.5cm×5.5cm, which presented as round, oval or irregular in shape. The features of shallow lobulation, smooth margin, spicule-like process and heterogeneous density existed in 13 cases, and smooth margin homogenous density in 2 cases. 1 case showed internal grit-like calcification, 1 case showed thick-wall cavities and 1 case showed thin-wall with typical “air-crescent sign”. After contrast moderately heterogeneous enhancement of solid portion existed in 9 cases, homogenous enhancement in 2 cases and ring-shaped enhancement in 1 case. Three cases demonstrated punctiform vascular-like enhancement in the edge and solid portion after 60 seconds enhanced MSCT. Lymph node enlargement in mediastinum or hilum of the same side in 10 cases, pleural involed in 4 cases, “pleural indentation sign” existed in 2 cases. Multiple planar reconstruction(MPR) could exactly display the mass spatial characteristic and relationship with normal lung field and pleura. Conclusion: Plain and enhanced CT(especially MSCT) with MPR were valuable methods to the diagnosis of LCLC.
2007, Vol. 18 
