Comparison of 3.0T high-resolution MRI and DSA of middle cerebral artery atherosclerotic stenosis
HUANG Jun1, GUO Fu-qiang1, CHEN Shi-yue2, LIU Qi2
1. Department of Radiology, People’s Liberation Army No. 425 Hospital, Sanya Hainan 572000, China;2. Changhai Hospital, the 2nd Military Medical University, Shanghai 200433, China
Abstract：Objective: To compare 3.0T HR-MRI and DSA for the diagnosis of the middle cerebral artery M1 segment stenosis and discuss the clinical value and limitation of 3.0T HR-MRI in the diagnosis of middle cerebral artery atherosclerotic stenosis. Methods: Sixty-seven patients with ischemic cerebrovascular disease received both 3.0T HR-MRI and DSA examinatin. The sensitivity, specificity, accuracy, negative predictive value and positive predictive value of 3.0T HR-MRI diagnosis of middle cerebral artery stenosis were calculated using DSA as the golden standard. The clinical value of 3.0T HR-MRI diagnosis of intracranial vascular stenosis was evaluated． Results: Among 67 patients, 124 blood vessels showed the same condition as DSA, with the coincidence rate of 92.5%. The sensitivity, specificity, accuracy, positive predictive value, negative predictive value in 3.0T HR-MRI diagnosis of mild degree, moderate degree, severe degree stenosis and obliteration were 80%, 99.2%, 98.5%, 80%, 99.2%; 95.7%, 98.5%, 91.4%, 84.6%, 98.5%; 84%, 98.2%, 91.4%, 80.8%, 95.7%; 100%, 100%, 100%, 100%, 100%． For mild, moderate, severe degree stenosis, and occlusion of MCA rates according to Youden index were 79.2%, 94.2%, 82.2%, 100%; Kappa values were 0.792, 0.788, 0.895, 1． Conclusions: 3.0T HR-MRI evaluation of middle cerebral artery atherosclerotic stenosis has a high sensitivity, specificity and accuracy, with a good relevance with DSA. 3.0T HR-MRI can replace DSA to become a general choice for cerebrovascular stenosis screening examination．
2014, Vol. 25 
