探讨18F-FDG PET/CT在非小细胞肺癌放射治疗靶区勾画及#br#
临床分期中的价值

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Abstract Objective: To explore the application value of 18F-FDG PET/CT in delineation of radiotherapy target area and clinical stage in non-small cell lung cancer, and to provide a basis for formulation of treatment plan. Methods: Eighty patients confirmed with non-small cell lung cancer by cytology or pathology and suitable for radiotherapy from January 2014 to November 2015 in our hospital were enrolled in this study. In which, 51 cases were squamous cell carcinoma, 29 cases were adenocarcinoma. Breast enhancement CT and 18F-FDG PET/CT were performed in all patients, and GTVPET/CT and GTVCT were determined, and the difference was compared statistically. Results: ①GTVPET/CT((20.74±15.57) cm3) was 24.16% smaller than GTVCT((26.33±17.31) cm3), and the difference was statistically significant(P<0.05). ②GTVCT and GTVPET/CT were (27.85±15.79) cm3 and (22.35±14.06) cm3 respectively in squamous carcinoma group, GTVCT and GTVPET/CT were (25.46±18.21) cm3 and (19.83±16.44) cm3 respectively in adenocarcinoma group, and GTVCT were bigger than GTVPET/CT in both groups, and the difference was significant statistically(P<0.05). ③18F-FDG PET/CT changed the clinical stage in 46 patients(57%) in all patients, in which 35 cases were up regulated, 11 cases were down regulated. Conclusion: 18F-FDG PET/CT can be helping in distinguishing tumor tissue with the surrounding atelectasis or inflammation, and in delineation of radiotherapy target area, and also in accurate clinical staging.

Key words： Carcinoma, non-small-cell lung Fluorodeoxyglucose F18 Positron-emission tomography

Received: 21 June 2016

PACS:	Ｒ734.2
	Ｒ817.4

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	Articles by authors
	ZHAO Xiao-xiao
	RUAN Qiao
	XIE Xin-li
	CHANG Wei
	ZHAO Su-dan
	ZHAO Xi-tong
	HAN Xing-min

Cite this article:

ZHAO Xiao-xiao,RUAN Qiao,XIE Xin-li, et al. Application value of 18F-FDG PET/CT in delineation of radiotherapy target area and#br# clinical stage in non-small cell lung cancer[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(3): 188-192.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2017/V28/I3/188

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