术前粗针活检低估的乳腺导管内原位癌的超声、钼靶及临床病理特征分析

doi:DOI:10.12117/jccmi.2019.04.008

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Abstract Objective: To explore the ultrasonographic, molybdenum target mammography and clinicopathological features of the lesions with invasive carcinoma which were diagnosed as ductal carcinoma in situ(DCIS) by preoperative core needle biopsy, so as to evaluate the possibility of invasive components in DCIS before operation, and to help better formulate the surgical and therapeutic plan of DCIS. Methods: Seventy-eight lesions diagnosed as DCIS by preoperative core needle biopsy and resected by surgery were retrospectively analyzed. According to the pathological results after operation, they were divided into two groups(DCIS group and DCIS-Ⅰ group) for descriptive statistics and regression analysis. Results: Of the 78 lesions, 45(57.6%) were confirmed as DCIS and 33(37.9%) were found to have invasive components. Ki-67 overexpression(OR=2.870, 95%CI=1.065~7.730), EGFR positive(OR=4.833, 95%CI=1.083~21.561), ultrasound-detected microcalcification (OR=4.533, 95%CI=1.627~12.633) were correlated with predicting invasive components in DCIS, ultrasound-detected microcalcification(OR=4.746, 95%CI=1.263~17.828) was the most relevant factor in predicting invasive components in DCIS. Conclusion: For the lesions diagnosed as DCIS by preoperative core needle biopsy, if there are high expression of Ki-67, positive EGFR and microcalcification in ultrasound, we should be alert to the high risk of invasive components in DCIS.

Key words： Carcinoma, ductal, breast Ultrasonography Radiography

Received: 05 June 2018

PACS:	Ｒ737.9
	Ｒ445.1
	Ｒ814.41

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	ZHOU Han-xiao
	WANG Hong-qiao

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ZHOU Han-xiao,WANG Hong-qiao. Ultrasound, molybdenum target mammography and clinicopathological characteristics of ductal carcinoma in situ of the breast underestimated by preoperative core needle biopsy[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(4): 257-260.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2019.04.008 OR http://www.jccmi.com.cn/EN/Y2019/V30/I4/257

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