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期刊信息  
创刊日期：1990年
主管单位：中国人民共和国卫生部
主办单位：中国医学影像技术研究会
　　　　　中国医科大学
承办单位：中国医科大学附属盛京医院
　　　　　辽宁省医学影像学会
编辑出版：《中国临床医学影像杂志》
　　　　　编辑部
刊　　期：月刊
2017 Vol. 28, No. 1
Published: 2017-01-20
 
1 Relationship between thrombosis and vascular responsibility in acute cerebellar ischemic stroke by 3.0 Tesla SWI and MRA
XU Kai-xi, CHEN Xin-jian, ZUO Tao-sheng, MA Xian-jun, BIAN Guang-rong, WANG Jin, HU Fang-yun, WANG Hui
Objective: To investigate the effects of 3.0T magnetic resonance susceptibility weighted imaging(SWI) and MRA in thrombosis and according vascular responsibility in acute cerebellar ischemic stroke and the clinical application value. Methods: Thirty cases of acute ischemic stroke in cerebellum(<72 h) were enrolled with conventional brain MRI, MRA and SWI. Susceptibility vessel sign(SVS) on SWI and arterial stenosis or occlusion were analysed and correlated. Results: Hyperintensity on DWI and hypointensity on ADC maps were shown in all 30 cases of acute cerebellar ischemic stroke. Among all, 70%(21 cases) were from inferior posterior cerebellar artery, 23.3%(7 cases) were from anterior posterior cerebellar artery, and 6.7%(2 cases) were from anterior cerebellar artery. MRA showed cerebellar arterial stenosis or occlusion in 14 cases(46.7%), but failed in the rest 16 cases(53.3%). SVS were shown in 26 cases(86.7%) with double SVS in 7 cases, while the 4 cases had no SVS(13.3%). SWI and MRA showed significant difference in displaying SVS in cerebellar arteries and responsible vessels(χ2=10.800, P=0.002). Conclusion: SWI and MRA showed obvious consistency in displaying responsible vessels in acute cerebellar ischemic stroke. SWI was much better than 3D-TOF-MRA in detecting small arterial thrombosis.
2017 Vol. 28 (1): 1-4 [Abstract] ( 845 ) HTML (1 KB)  PDF  (0 KB)  ( 215 )
5 Preliminary study of cerebellar magnetic resonance spectroscopy on simple febrile convulsion in children
ZOU Jing, XU Ai-hua
Objective: To explore changes in metabolite levels of cerebellum for children with simple febrile convulsion (SFC) by magnetic resonance spectroscopy(MRS). Methods: Nine children diagnosed SFC and seven age-matched healthy children were enrolled. Multi-voxel chemical shift imaging was performed. The metabolite ratios of cerebellum involving NAA/Cr, NAA/Cr2, Cho/Cr, Cho/Cr2 and NAA/Cho were estimated. The Mann-Whitney U test was performed to compare the differences between the two groups. Lac peak was recorded and analysed between two groups and Fisher’s exact test was performed to compare the differences. Results: The ratio of NAA/Cr in cerebellum with SFC was found to be decreased compared to normal control subjects(0.91±0.12 vs 1.03±0.07, P=0.023). There was no statistical difference for the ratios of NAA/Cr2, Cho/Cr2, NAA/Cho(P>0.05). Lac peaks were detected in the cerebellum of five cases with SFC and no Lac peak was detected in the control group. The difference showed statistical significance(P=0.034). Conclusion: MRS is a useful tool for evaluating major changes in metabolite levels of brain and may contribute to evaluate the damage caused by SFC from the biochemical aspect.
2017 Vol. 28 (1): 5-7 [Abstract] ( 648 ) HTML (1 KB)  PDF  (0 KB)  ( 124 )
8 The study of DTI in acute cervical spinal injury with different ASIA grades
ZOU Zhi-meng1, DU Mei-ling1, LI Jun1, CAO Qing-yong1, LIAN Hui-xiu1, SHEN Xiao-jun1, WANG Bin2
Objective: To study the clinical value of DTI in acute spinal cord injury(SCI) with different ASIA grades. Methods: A retrospective analysis of 34 acute SCI patients with conventional MRI T2WI hyperintensity was made. All patients underwent MR-DTI examination in 48 hours. According to ASIA grades, we measured the values of  FA, ADC, λ∥, λ⊥in the injury area. We recruited 15 healthy volunteers of matched ages, and measured the same parameters in the corresponding level of C3/4~C5/6 intervertebral disc plane. Single factor analysis of variance(ANOVA) was applied to analyze the difference in DTI parameters in ASIA grade A to D. Independent sample t test was used to analyze DTI parameters in DWI image matching area(hyperintense on both DWI and T2WI) and mismatch area(isointense on DWI but hyperintense on T2WI) in the same patients. Results: The number of patients is 7 in grade A, 5 in grade B, 19 in grade C, and 13 in grade D. Compared with the healthy group, the A～D groups showed significant differences in FA, ADC, λ∥ and λ⊥(F=51.90, 13.30, 24.70, 13.01, P<0.001). Compared with grade B, C and D, the values of FA, ADC and λ∥ in grade A were significantly reduced by pairwise comparison(P<0.05). FA and λ∥ showed a downward trend as ASIA grade was reduced. ADC values increased in grade A, however decreased in grade B to D. As for λ⊥ elevation, by pairwise comparison, grade B showed significant difference from grade A, C and D(P<0.05). There was no significant difference between grade A, C or D in λ⊥ by pairwise comparison(P>0.05). DTT showed in injured area nerve fiber bundle swelling, distortion and interruption in grade A. The nerve fiber bundles were swelling, coarse and partially interrupted in grade B. Integrated nerve fiber bundles could be found in grade C and D. Comparing DWI match area with mismatch area, ADC, λ∥ decreased and λ⊥ increased significantly(P<0.05), whereas the changes of FA value had no difference(P＞0.05). DTT demonstrated that the nerve fiber bundle in DWI match area was interrupted. Conclusion: FA value and λ∥ value are sensitive indexes among different AISA grades in acute SCI. The lower the ADC value is, the more serious the injury is. DTT can display the position and injury extent of nerve fiber bundles, and provide more imaging evidence for clinical treatment.
2017 Vol. 28 (1): 8-11 [Abstract] ( 626 ) HTML (1 KB)  PDF  (0 KB)  ( 145 )
12 Value of ultrasonography in differential diagnosis and treatment of cervical lymph nodes
WANG Wen-li, HAN Ling-min
Objective: To explore the value of ultrasonography in differentiating malignant and benign cervical lymph nodes and guiding therapy. Methods: Seventy-three cases with cervical lymph nodes were retrospectively reviewed with ultrasonic images before and after pathological diagnosis. Follow-up of lymph node changes was performed on malignant cases. Results: Among all the patients, twelve cases were benign, seven cases were lymphoma and 54 cases were metastases. Among diverse imaging characteristics, some differentiation features included lymph node morphology, diameter, corticomedullary boundary and blood flow distribution. For lymph node metastasis and lymphoma, the changes of cervical lymph nodes during follow-up studies were easy and important observation indexes. Conclusion: Ultrasonography plays a simple, noninvasive, high efficient and economic role in diagnosis and differential diagnosis of cervical lymph nodes. It is also a good monitoring method for follow-up in patients with malignant cervical lymph nodes. Ultrasonography can be used as a routine examination method for cervical lymph nodes.
2017 Vol. 28 (1): 12-14 [Abstract] ( 726 ) HTML (1 KB)  PDF  (0 KB)  ( 199 )
15 The short-term prognosis analysis of papillary thyroid carcinoma under the pre- and post-operation changes of#br# serum thyroglobulin(Tg) and BRAFV600E gene mutation
LI Shuang, LIU Bao-ping, CHANG Wei, WANG Rui-hua, XIE Xin-li, CHENG Bing, HAN Xing-min, RUAN Qiao
Objective: To explore the short-term efficacy and prognosis analysis of 131I papillary thyroid carcinoma patients under the pre- and post-operation changes of serum thyroglobulin(Tg) and BRAFV600E gene mutation. Methods: Seventy-eight patients of papillary thyroid carcinoma were enrolled to measure the Tg and TgAb value one week before and one month after operation. Meanwhile, the patients were monitored after operation to figure out whether there was BRAFV600E gene mutation. The standards for good short-term efficacy and prognosis include less than 2 ng/mL Tg under stimulated state and negative results of neck Doppler ultrasound and whole body radioactive iodine scanning. Results: Among the 43 patients with a reduced post-operative Tg value compared with one week before operation, there were 6 patients(13.9％) with recurrence after 131I operation in half a year. Among the 35 patients with an increased or similar post-operative Tg value compared with pre-operation, there were 24 patients(68.6％) with recurrence after 131I operation in half a year. There was significant difference between two groups(P<0.05). Among the 53 patients with positive BRAFV600E gene mutation, there were 28 patients(49.1％) with recurrence after 131I operation in half a year. Among the 25 patients with negative BRAFV600E gene mutation, there were 4 patients(16.0％) with recurrence after 131I operation in half a year. There was significant difference between two groups(P<0.05). Among the 21 patients with a reduced post-operative Tg value compared with one week before operation and with negative BRAFV600E gene mutation, there were 2 patients(9.5％) with recurrence after 131I operation in half a year. Among the 32 patients with an increased or similar post-operative Tg value compared with pre-operation and positive BRAFV600E gene mutation, there were 23 patients(71.9％) with recurrence after 131I operation in half a year. There was significant difference between two groups(P<0.05). Conclusion: The prognosis of papillary thyroid carcinoma seems poor with no decreased post-operative Tg value or positive BRAFV600E gene mutation.
2017 Vol. 28 (1): 15-18 [Abstract] ( 769 ) HTML (1 KB)  PDF  (0 KB)  ( 175 )
19 Different expression of Galectin-3 and CK19 in benign and malignant follicular thyroid tumors by ultrasound-guided fine needle aspiration
JIA Li-qiong, PAN Jiong, LI Xiao-qiang
Objective: To explore the different expression of Galectin-3 and CK19 in benign and malignant thyroid follicular tumors by ultrasound-guided biopsy. Methods: Thirty-four patients with follicular thyroid carcinoma(FTC) and 40 patients with follicular adenoma(FA) were divided into FTC group and FA group respectively. The expression of Galectin-3 and CK19 in the specimens of ultrasound-guided fine needle aspiration cytopathology and in the pathological tissue were detected, analyzed and compared. The expression in the pathological tissue was considered as the gold standard, and then the sensitivity, specificity and accuracy of FNAC specimens to determine Galectin-3 and CK19 were analyzed. The relationship between Galectin-3, CK19 and clinical parameters of patients with FTC were also compared. Results: The expression of Galectin-3 and CK19 between FTC group and FA group were significantly different(Galectin-3：Z=－4.478, P=0.000, CK19：Z=－2.307, P=0.021). The sensitivity, specificity, and accuracy of Galectin-3 and CK19 in FNAC specimens were 85.7%, 76.3% and 81.3% plus 84.7%, 91.2% and 87.5%. The Galectin-3 expression showed no significant difference between the gender, age and tumor size in FTC patients(P>0.05). The positive rate of Galectin-3 in patients with lymph node metastasis(93.3%) and TNMⅢ+Ⅳ(100%) stage were significantly higher than that in patients without lymph node metastasis(63.2%) and TNMⅠ+Ⅱstage(66.7%). The difference was statistically significant(Stages: T=4.359, P=0.037; lymph node metastasis: T=4.242, P=0.039). The expression of CK19 had no significant difference between these clinical parameters(P>0.05). Conclusion: The expression of Galectin-3 and CK19 in FNAC specimens from FTC patients was significantly higher than that in patients with FA, which could help to differentiate FTC and FA in clinics.
2017 Vol. 28 (1): 19-22 [Abstract] ( 659 ) HTML (1 KB)  PDF  (0 KB)  ( 149 )
23 Retrospective analysis on ultrasonic and clinicopathologic features of triple and#br# non-triple negative breast cancer
JIA Zhi-ying, ZHANG Yin-hua, LENG Xiao-ling, MA Fu-cheng
Objective: To investigate the ultrasonic features and clinicopathologic characteristics of the triple negative breast cancer(TNBC) and non-triple negative breast cancer(NTNBC)． Methods: Forty-six TNBC and 50 NTNBC cases were analyzed retrospectively, to compare the difference of ultrasonograms and clinicopathologic features. Results: The average age of TNBC group was 48.49±11.66 years old, the mean size of tumors was (4.69±3.78) cm, and the sign of lobular tumor edge frequently occurred(P<0.01). The average age of NTNBC group was 46.83±9.12 years old, the mean size of tumors was (2.61±0.91) cm. In the NTNBC group, the signs of spiculation(P＜0.01), micro-calcification(P<0.01) and posterior echo attenuation(P<0.05) showed statistically significant difference. There was no statistically significant difference in axillary lymph node metastasis rate. Conclusion: The features of ultrasonograms and clinicopathology were different between NTNBC and TNBC, which had their own characteristics.
2017 Vol. 28 (1): 23-26 [Abstract] ( 824 ) HTML (1 KB)  PDF  (0 KB)  ( 162 )
27 Relationship of CT imaging features and positive bronchoalveolar galactomannan for#br# invasive pulmonary aspergillosis
GONG Zheng1, GONG Ping2, JIN Zhu1, ZHANG Ling-yun1, WANG Yong-quan1,XIANG Guang-ming1, GAO Bao-an1, CHEN Shi-xiong1
Objective: To evaluate relationship between CT imaging features and positive bronchoalveolar galactomannan(GM) for invasive pulmonary aspergillosis(IPA). Methods: One hundred and twenty patients with IPA were enrolled in this study． The levels of GM were measured in bronchoalveolar lavage(BAL)． Univariate logistic regression analysis was performed with GM in BAL and involved lung lobe number, existence of air crescent sign and halo sign． Result: The positive rate of GM in BAL is correlated with the number of involved lung lobes and existence of halo sign on CT. Conclusion: GM in BAL may be an important marker for diagnosing IPA, and GM in BAL is correlated with CT features.
2017 Vol. 28 (1): 27-29 [Abstract] ( 756 ) HTML (1 KB)  PDF  (0 KB)  ( 210 )
30 Clinical value of 18F-FDG PET/CT in puncture site selection for multiple lung lesions
YANG Chao, QIU Jian-rong, ZHANG Ji, LEI Juan, ZHANG Hong-wen
Objective: To investigate the clinical value of 18F-FDG PET/CT puncture site selection for multiple lung lesions. Method: A retrospective analysis of 164 patients with multiple lung lesions was performed, including 60 patients with preoperative 18F-FDG PET/CT guided core needle biopsy and the rest 104 patients with contrast-enhanced CT guided biopsy. Results: Among the 60 patients with 18F-FDG PET/CT guided core needle biopsy, fifty-nine had definite pathological diagnosis. The rates of technical success in acquiring samples was 98.3%, with 57 biopsy sites in the area of maximum SUV. In 104 patients contrast-enhanced CT guided biopsy, eighty-six had definite pathological diagnosis, the rate of technical success in acquiring samples was 82.7%. Difference of the two data sets was statistically significant(χ2=7.63, P＜0.05). Conclusions: Compared to CT-guided biopsy, 18F-FDG PET/CT has higher diagnostic accuracy in selecting SUVmax areas in lesions as the puncture site.
2017 Vol. 28 (1): 30-34 [Abstract] ( 824 ) HTML (1 KB)  PDF  (0 KB)  ( 179 )
35 Value of chest plain CT scan in the diagnosis of chronic mountain sickness
CAO Cheng-ying, CHEN Hong, WANG Sheng-yuan, LUO Huan
Objective: To investigate the relationship between the widening of main pulmonary arteries, the CT value of  left and right ventricular cavity and the increase of hemoglobin in chronic mountain sickness, as well as their diagnostic value of chronic mountain sickness. Methods: A retrospective analysis was made in 53 cases of chronic mountain sickness who lived at an altitude between 2 500~4 600 m. By comparison with normal chest CT scan, a retrospective analysis was made in the widening of main pulmonary arteries, the CT value of left and right ventricular cavity and the difference between the CT values of the left ventricle and interventricular septum. An independent sample t test was used between different groups. The linear regression correlation analysis was made with the recent hemoglobin content. Results: In the 53 cases of chronic mountain sickness, the CT values of left and right ventricular cavities((56.14±6.27) HU, (56.14±6.27) HU) were increased. The difference between the CT values of left ventricle and the interventricular septum((12.17±4.09) HU) increased. Compared with the CT values of left and right ventricular cavities((38.02±3.42) HU, (38.85±3.86) HU) and the difference of CT values between left ventricle and interventricular septum((2.02±3.07) HU) in normal controls, as t values were 18.470, 16.976 and 14.449 with statistically significant difference(P<0.01). The CT values of left and right ventricular cavities and the CT value difference between left ventricular cavity and interventricular septum were positively correlated with the hemoglobin content in patients with chronic mountain sickness. The r values were 0.723, 0.701 and 0.501 respectively with significant difference(P<0.01). The main pulmonary arteries in chronic mountain sickness were widened, t value was 16.411 with statistical significance(P<0.01) between different groups. Conclusion: The widened diameters of main pulmonary artery, increased density of left and right ventricular cavity and the enlarged difference between left ventricle and interventricular septum on plain CT scan, are  significantly correlated in chronic mountain sickness, which can provide valuable information for clinical diagnosis.
2017 Vol. 28 (1): 35-38 [Abstract] ( 775 ) HTML (1 KB)  PDF  (0 KB)  ( 237 )
39 The value of diffusion-weighted imaging based on monoexponential and biexponential model in#br# differentiating benign and malignant hepatic hypervascular lesions
YING Ming-liang, SHU Jin-er, PAN Jiang-feng, LU Jin-hua, PAN Yong-hao, JIANG Yang, FU Jian-fei
Objective: To investigate the value of monoexponential and biexponential model diffusion-weighted imaging in differentiating benign and malignant hepatic hypervascular lesions. Materials and Methods: Forty-four patients(48 lesions) with pathologically or clinically confirmed hepatic hypervascular lesions, were analyzed retrospectively and categorized into benign and malignant groups. All patients underwent routine MR scan and parallel multi b value DWI(b=0, 50, 100, 150, 200, 400, 600, 800, 1 000, 1 200 s/mm2) to obtain the monoexponential modeling value ADC(b=0, 800 s/mm2) and IVIM parameters of biexponential modeling: fast diffusion coefficient Dfast value, slow diffusion coefficient Dslow value and fast diffusion component percentage of F value. Independent two-samples t test was used to compare ADC value, Dfast value, Dslow value and F value between hypervascular benign and malignant groups. Receiver operating characteristic(ROC) curve was used to evaluate those parameters in differentiating benign and malignant lesions and identifying hyper- or hypovascular. Results: The ADC, Dslow value of benign group((1.75±0.68)×10-3 mm2/s, (1.61±0.39)×10-3 mm2/s) were statistically higher than those of malignant group((1.21±0.21)×10-3 mm2/s, (0.99±0.19)×10-3 mm2/s). The Dfast and F values of benign group((30.93±20.00)×10-3 mm2/s, (34.01±11.48)%) were higher than those of malignant group((28.56±18.56)×10-3 mm2/s, (31.37±9.86)%) with no statistical significance. The sensitivity, specificity, accuracy and the area under ROC in differentiating benign and malignant hypervascular lesions were 80.76%, 86.36%, 83.33%, 0.875; 92.30%, 95.45%, 95.83%, 0.945; 46.12%, 72.72%, 60.87%, 0.534, 53.84%, 68.18%, 60.41%, 0.545 by using a threshold ADC, Dslow, Dfast, F values of 1.35×10-3 mm2/s, 1.25×10-3 mm2/s, 20.61×10-3 mm2/s, 32.36% respectively. Conclusion: The ADC value obtained with monoexponential modeling and Dslow obtained with biexponential modeling are useful in differentiating benign and malignant hepatic hypervascular lesions, and Dslow has the highest diagnostic efficacy.
2017 Vol. 28 (1): 39-43 [Abstract] ( 864 ) HTML (1 KB)  PDF  (0 KB)  ( 206 )
44 Value of spectrum curve from single-source dual-energy noncontrast CT imaging for #br# identifying atypical small hepatocellular carcinnoma from hepatic perfusion disorders
XU Ming-zhe, LIU Ai-lian, SUN Mei-yu, LIU Yi-jun, LI Ye
Objective: To assess the spectral curve from noncontrast CT imaging in differentiating atypical small hepatocellular carcinnoma(SHCC) from hepatic perfusion disorders(HPD) with single-source dual-energy CT. Methods: Thirty-two histopathologically or clinically proven SHCC and HPD patients, who underwent spectral CT enhancement scanning using spectrum imaging modality(GSI) were retrospectively enrolled with 35 lesions, including 16 SHCC and 19 HPD. The atypical SHCCs were hyperattenuating in arterial phase and nearly isodense in portal venous and equilibrium phases. On polychromatic images(QC images), CT value(CT(QC) value) of SHCC, HPD and appropriate background were measured in noncontrast and arterial phase, and then on monochromatic(40 keV and 140 keV) images, thus the slope of the energy spectrum was calculated. The data from two observers were analyzed with intra-class correlation coefficients(ICC） to assess inter-observer agreement. The differences of CT(QC) value and spectral curve slope between SHCC and liver background, HPD and appropriate background were compared by paired t-test. The differences of CT(QC) value and spectral curve slope between SHCC and HPD on noncontrast and arterial phase images were compared by independent t-test. Results: The inter-observer agreements were good(ICC>0.75). In arterial phase, there were no differences of CT(QC) value or spectral curve slope between SHCC and HPD. On unenhanced imaging, there were no differences of CT(QC) value between SHCC and background, HPD and background, or SHCC and HPD. However, there were significant differences of spectral curve slope between SHCC and background, SHCC and HPD((0.19±0.12) vs (0.00±0.12), (0.19±0.12) vs (0.04±0.17), P<0.05). There was no difference of spectral curve slope between HPD and background. Conclusion: The single-source dual-energy CT noncontrast imaging provides a new convenient, safe and reliable method on the basis of spectral curve features to identify atypical SHCC and HPD which were difficult to differentiate on three phase enhanced imaging by conventional CT.
2017 Vol. 28 (1): 44-48 [Abstract] ( 826 ) HTML (1 KB)  PDF  (0 KB)  ( 148 )
48 Prenatal echocardiographic findings of Berry syndrome: report of one case
MIAO Wei, JIANG Yi-na, WANG Cui-cui
2017 Vol. 28 (1): 48-48 [Abstract] ( 663 ) HTML (1 KB)  PDF  (0 KB)  ( 217 )
49 The application value of IVIM-DWI for diagnosing and differentiating pancreatic cancer and neuroendocrine tumor
MA Wan-ling, ZHAO Wei-wei, HUAN Yi, WEI Meng-qi, REN Jing, YANG Yong, ZHANG Jin-song,PAN Qi, ZHANG Guang-wen, DONG Jun-qiang
Objective: To explore the optimal quantitative parameters obtained from IVIM-DWI for diagnosing and differentiating pancreatic cancer and neuroendocrine tumor. Methods: Subjects comprised 22 patients with pancreatic cancer and 17 patients with pancreatic neuroendocrine tumors, All the patients were confirmed by surgery. Pancreas multiple b value DWI was performed using GE Discovery MR750 3.0T scanner. Apparent diffusion coefficient(ADC), pure diffusion constant(D), pseudodiffusion coefficient(D*) and perfusion fraction(f) were calculated by using IVIM model. Parameters obtained from IVIM-DWI were tested by One-Way ANOVA. Results: ADC and f values of pancreatic cancer were lower than non-cancerous pancreatic tissue(0.803×10-3 mm2/s vs 0.974×10-3 mm2/s; 54.527% vs 64.486%, respectively). D of pancreatic cancer was higher than non-cancerous pancreatic tissue(0.659×10-3 mm2/s vs 0.535×10-3 mm2/s). D is superior to ADC and f for the differentiation between pancreatic cancer and non-cancerous pancreas. ADC, D and f values of pancreatic neuroendocrine tumor were higher than non-tumorous pancreatic tissue(0.933×10-3 mm2/s vs 0.753×10-3 mm2/s; 0.549×10-3 mm2/s vs 0.429×10-3 mm2/s; 67.275% vs 59.655%, respectively). ADC is superior to D and f for the differentiation between pancreatic neuroendocrine tumor and non-tumorous pancreas. ADC, D* and f values of pancreatic cancer were lower than pancreatic neuroendocrine tumor(0.803×10-3 mm2/s vs 0.933×10-3 mm2/s; 4.852×10-3 mm2/s vs 11.301×10-3 mm2/s; 54.527% vs 67.275%, respectively). D* is superior to ADC and f for the differentiation between pancreatic cancer and neuroendocrine tumor. D* value of pancreatic cancer was significantly lower than G2～3 grade pancreatic neuroendocrine tumor(4.852×10-3 mm2/s vs 11.937×10-3 mm2/s). Conclusion: Quantitative parameters ADC, D, D* and f obtained from IVIM-DWI can diagnose and differentiate pancreatic cancer, neuroendocrine tumor and non-cancerous pancreatic tissue. IVIM-DWI may be a promising and non-invasive tool for diagnosing and differentiating pancreatic carcinoma and neuroendocrine tumor.
2017 Vol. 28 (1): 49-54 [Abstract] ( 937 ) HTML (1 KB)  PDF  (0 KB)  ( 204 )
55 Correlation of standardized uptake value on fluorodeoxyglucose PET/CT with apparent diffusion coefficient#br# in patients with rectal adenocarcinoma
GAO Jing-jing, LI Shao-dong, DAI Yue, XU Hui-ting, WANG Qi
Objective: The aim of this study was to assess the correlation of maximum standardized uptake values(SUVmax) and minimum apparent diffusion coefficient(ADCmin) with pathological grade respectively, and assess the quantitative relationship between SUVmax and DWI ADC values in rectal adenocarcinoma. Methods: Preoperative PET/CT and pelvic MRI imaging of thirty-five patients with rectal adenocarcinoma were retrospectively analysed. After measurement of SUVmax and ADCmin, correlation analysis was conducted. Results: The mean SUVmax were significantly different among groups classified by histologic differentiation grades. The differences of mean SUVmax among T-stage groups were not significant(P>0.05). Tukey’s post hoc test showed statistical differences of mean SUVmax between well and moderately differentiated groups, well and poorly differentiated groups(P<0.05). The ADCmin was significantly different when comparing groups classified by histologic differentiation grade and T stage. The mean ADCmin of different groups  differed significantly with each other(P<0.05). In the T-stage groups, only the mean ADCmin of stage T4 tumor was significantly different from that of each the other three T stages(P<0.05). A significantly negative correlation was found between SUVmax and ADCmin(r=-0.540; P<0.05). Conclusion: SUVmax and ADCmin values can reflect pathologic features of rectal cancer. The significantly negative correlations between SUVmax and ADCmin suggest an association between tumor cellularity and metabolic activity in rectal adenocarcinoma.
2017 Vol. 28 (1): 55-59 [Abstract] ( 874 ) HTML (1 KB)  PDF  (0 KB)  ( 219 )
60 Value of multiparametric magnetic resonance imaging in prostate cancer detection based on#br# prostate imaging reporting and data system version 2
ZENG Hao1, YANG Guo-qing1, FU Quan-shui1, CHEN Hong1, ZHAO Lin-wei1, NIU Xiang-ke2
Objective: To evaluate interobserver agreement and diagnosis value with the use of updated Prostate Imaging Reporting and Data System version 2(PI-RADS v2) for the detection of prostate cancer. Methods: The multiparametric MRI images of 176 histologically proven prostate lesions were analyzed retrospectively. Prostate biopsy was performed under the guidance of TRUS. Biopsied lesions were evaluated according to the PI-RADS v2 and compared with histopathological findings by two observers blindly. Cohen’s Kappa statistics were calculated to evaluate the consistency of the two observers and the area under the receiver operating characteristic curve(ROC-AUC) was calculated to evaluate the diagnosis value of PI-RADS v2. Results: Interobserver agreement for peripheral zone and transition zone lesions were 0.63 and 0.60, respectively. For peripheral zone cancer and transition zone cancer, the sensitivity, specificity, PPV, and NPV were 85%, 79%, 76%, 87% and 81%, 69%, 64%, 72%, respectively. Conclusion: The application of updated PI-RADS v2 provides high interobserver agreement for detecting peripheral zone and transition zone lesions. Futhermore, PI-RADS v2 can achieve relatively high sensitivity and NPV in the diagnosis of peripheral zone cancer. For transition zone cancer, although PI-RADS v2 can achieve relatively high sensitivity, the specificity needs to be improved.
2017 Vol. 28 (1): 60-63 [Abstract] ( 709 ) HTML (1 KB)  PDF  (0 KB)  ( 195 )
64 Application in head-neck CTA based on IMR with low tube voltage and low rate injection of contrast medium
GAO Si-zhe, ZHANG Bin, ZHAO Fu-xin, GUO Wen-li
Objective: To investigate the clinical use of 256-slice spiral CT in the diagnosis of head and neck artery disease in CTA combined with low-tube-voltage and low rate injection of contrast medium by IMR reconstruction. Methods:   Sixty patients who would perform head-neck CTA were enrolled and divided into two groups randomly. CTA was performed in group A using normal tube voltage(120 kV) and normal injection rate of contrast medium(5 mL/s) by iDose4 reconstruction. Group B received CTA by low-tube-voltage(100 kV) and low injection rate of contrast medium(4 mL/s) with IMR reconstruction. Quantitative measurements of CT value, image noise and contrast-to-noise ratio(CNR) were measured in either group. The t-test was used to compare objective evaluation indices(noise, CNR) and radiation dosage between the two groups. χ2-test was used to compare subjective evaluation of image quality(contrast, sharpness and subjective noise) between the two groups. A level of P＜0.05 was considered statistically significant. Results: There were significant differences in objective noise and CNR between the two groups(P＜0.01). Group B showed better subjective image quality. Compared to group A, group B showed better subjective scores of contrast and noise, and slightly worse score of sharpness with no significence(P>0.05). The effective dose(ED) of group B((0.84±0.03) mSv) was 41% lower compared to group A((1.43±0.06) mSv). Conclusion: Compared with iDose4, iterative model reconstruction technique can provide 41% ED reduction in head-neck CTA by 256 MSCT with satisfactory image quality.
2017 Vol. 28 (1): 64-67 [Abstract] ( 691 ) HTML (1 KB)  PDF  (0 KB)  ( 192 )
68 The progression of transcervical ultrasonography in nasopharyngeal carcinoma detection
WANG Dong-lin, WU Tang-na, JING Xiang-xiang
The development of ultrasound imaging technology in head and neck section has played an increasingly important role in clinical diagnosis. In patients with nasopharyngeal carcinoma, the ultrasound can detect the soft tissue and supply high resolution photography in the lateral pharyngeal wall and partial posterior pharyngeal wall, and then define the relationship between the tumor and ipsilateral parapharyngeal space, which provides a new method in the imaging diagnosis area. This article reviews the development of transcervical ultrasonography in its clinical application in nasopharyngeal carcinoma.
2017 Vol. 28 (1): 68-69 [Abstract] ( 735 ) HTML (1 KB)  PDF  (0 KB)  ( 402 )
70 Ultrasonographic findings of primary liver paraganglioma: report of one case
LI Qing, ZENG Wang, SUN Yan
2017 Vol. 28 (1): 70-71 [Abstract] ( 874 ) HTML (1 KB)  PDF  (0 KB)  ( 156 )
71 Von Hippel-Lindau syndrome: report of one case and literature review
ZHONG Ling-shan, CAO Zhen-dong
2017 Vol. 28 (1): 71-73 [Abstract] ( 686 ) HTML (1 KB)  PDF  (0 KB)  ( 193 )
73 Primary urethral clear cell adenocarcinoma: report of one case
WU Meng-nan1, REN Ming-da2, HUANG Zhi-ming1, HAN Zhi-jiang3
2017 Vol. 28 (1): 73-75 [Abstract] ( 739 ) HTML (1 KB)  PDF  (0 KB)  ( 201 )
75 Oblique vaginal septum syndrome: report of one case and literature review
HE Ai, FENG Ping-yong
2017 Vol. 28 (1): 75-76 [Abstract] ( 614 ) HTML (1 KB)  PDF  (0 KB)  ( 200 )
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