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期刊信息

创刊日期：1990年
主管单位：中国人民共和国卫生部
主办单位：中国医学影像技术研究会
　　　　　中国医科大学
承办单位：中国医科大学附属盛京医院
　　　　　辽宁省医学影像学会
编辑出版：《中国临床医学影像杂志》
　　　　　编辑部
刊　　期：月刊

2020 Vol. 31, No. 7 Published: 2020-07-20

	457	Genes associated with white matter microstructure abnormality in schizophrenia
		YANG Bing-bing1, ZHANG Xue1, ZHUO Chuan-jun2, LIU Feng1, QIN Wen1, YU Chun-shui1
		DOI: 10.12117/jccmi.2020.07.001
		Objective: To investigate the mean kurtosis(MK) changes in patients with schizophrenia and to analyze correlation of gene expression level with MK in order to explore genes associated with white matter microstructure abnormality in schizophrenia. Methods: Ninety-four schizophrenia patients and 91 healthy controls were recruited to undergo a diffusion kurtosis imaging(DKI). Subsequently, quantitative map of MK for each subject was calculated. MK difference between patients with schizophrenia and healthy controls was compared using voxel-based analysis(VBA). For each brain tissue sample, expression profiles of 196 schizophrenia risk genes were extracted from six donated brains of the Allen Human Brain Atlas(AHBA). Genes associated with MK change in schizophrenia were identified by performing sample-wise spatial correlations between expression levels of each gene and case-control MK difference. Results: Relative to healthy controls, patients with schizophrenia had decreased MK mainly in the white matter of prefrontal lobe, corona radiata, internal capsule and corpus callosum. We found that expression levels of 16 genes had showed significant sample-wise spatial correlations with MK changes in schizophrenia. These genes were functionally enriched for calcium ion homeostasis and transmembrane transport, inositol trisphosphate metabolic process and cell-cell junction. Conclusion: This study provides a set of genes possibly associated with MK change in schizophrenia, which could be used as candidate genes to explore biological mechanisms underlying the structural impairments of white matter in schizophrenia.
		2020 Vol. 31 (7): 457-461 [Abstract] ( 1266 ) HTML (1 KB) PDF (0 KB) ( 51 )

	462	MR diagnosis and differential diagnosis of infratentorial ganglioglioma
		HUANG Cong1, ZHANG Heng-sheng1, JIANG Gui-hua2, ZHAO Bang1, ZHOU Xing-shun1, LUO Jun-de1
		DOI: 10.12117/jccmi.2020.07.002
		Objective: To analyze the MR findings of infratentorial ganglioglioma(GG) in order to improve the recognition and the diagnostic rate before operation. Methods: Retrospective analysis of the clinical, pathological and MR data of 8 cases of infratentorial GG after surgery and pathology. Results: All the lesions were located in the infratentorial brain parenchyma, involving the middle cerebellar peduncles, adjacent brain stem and cerebellar hemisphere. The shape of the focus was irregular and the boundary was unclear. T1WI mainly showed hypointensity or slightly hypointensity, T2WI and T2 FLAIR showed slightly hyperintense or hyperintense, and DWI mainly showed isointense or slightly hypointensity, anaplastic GG DWI may show uneven hyperintense. The enhancement is non-uniform in the shape of a strip or strip. There were different degrees of edema zone around the tumor, and the ipsilateral cerebellar hemisphere was accompanied with cerebral cortex atrophy. The main metabolites of the tumor: NAA peak decreased, Cho peak increased, Cr peak decreased slightly, Cho/Cr increased and Cho/NAA increased. Conclusion: The MR manifestation of infratentorial GG is different from that of supratentorial and has its characteristic manifestations. When it is found that the ipsilateral cerebellar cortex is atrophied, the possibility of this disease should be considered.
		2020 Vol. 31 (7): 462-465 [Abstract] ( 1218 ) HTML (1 KB) PDF (0 KB) ( 46 )

	466	Abnormal functional connectivity of the insula in type 2 diabetes mellitus: a resting-state functional MRI study
		WANG Man1, ZHANG Dong-sheng2, QI Fei1, SU Yu1, XIE Qing-ming1, TANG Min2, ZHANG Xiao-ling2
		DOI: 10.12117/jccmi.2020.07.003
		Objective: To investigate whether type 2 diabetes mellitus(T2DM) causes abnormal functional connectivity between the insula and the whole brain and its role in the neural mechanism of T2DM brain injury. Methods: A total of 33 patients with T2DM and healthy subjects(HC) matched with demographic data were included. All subjects underwent resting-state fMRI and neuropsychological tests to observe the difference in functional connectivity between the insula and the whole brain between the two groups, and the mean value of functional connections of significantly different brain regions were extracted. Then the correlation between the extracted mean value of functional connections and clinical data and neuropsychological evaluation was analyzed. Results: Compared with HC, the insula showed decreased functional connectivity between bilateral inferior frontal gyrus, right superior temporal gyrus, left angular gyrus and left cerebellum in T2DM patients, and no brain areas with enhanced functional connections were found. Moreover, the functional connectivity between the insula and the right inferior frontal gyrus in T2DM patients was negatively correlated with HbA1c(r=-0.379, P=0.035). Conclusion: There is a wide range of functional connectivity abnormalities between the insula and whole brains of T2DM patients, which may be the neurological basis of auditory and visual spatial function impairment. Continuous high glucose status may cause IC function impairment in T2DM patients.
		2020 Vol. 31 (7): 466-469 [Abstract] ( 1107 ) HTML (1 KB) PDF (0 KB) ( 40 )

	470	Diagnostic value of American College of Radiology and Kwak thyroid imaging reporting and data system(TI-RADS) combined with contrast-enhanced ultrasound on thyroid nodules
		MA Hui-fang1, XUE Gai-qin2
		DOI: 10.12117/jccmi.2020.07.004
		Objective: To compare the diagnostic value of thyroid imaging reporting and data system made by American College of Radiology(ACR TI-RADS), Kwak TI-RADS combined with contrast-enhanced ultrasound(CEUS) on thyroid nodules. Methods: Preoperative conventional ultrasound images and contrast-enhanced ultrasound images of 111 patients with thyroid nodules(in total of 165 nodules) were retrospectively analyzed. The nodules were classified with ACR TI-RADS, Kwak TI-RADS and TI-RADS after CEUS, and receiver operating characteristic curve were constructed with surgical pathological results as “golden standard”. Diagnostic value of three methods on thyroid nodules was analyzed and diagnostic efficiency was compared. Results: The sensitivity, specificity, accuracy and AUC of Kwak TI-RADS in diagnosing benign and malignant thyroid nodules respectively were 78.45%, 97.96%, 84.24%, 0.924. The sensitivity, specificity, accuracy and AUC of ACR TI-RADS in diagnosing benign and malignant thyroid nodules respectively were 81.90%, 83.67%, 82.42%, 0.878. The difference of specificity and AUC was statistically significant. The sensitivity, specificity, accuracy and AUC of Kwak TI-RADS after CEUS in diagnosing benign and malignant thyroid nodules were respectively 87.07%, 81.63%, 85.45% and 0.926, and the difference between each indicator compared with Kwak TI-RADS was not statistically significant. Conclusion: ACR TI-RADS and Kwak TI-RADS both have high diagnostic value for thyroid nodules, and Kwak TI-RADS has better specificity, especially for the benign nodules.
		2020 Vol. 31 (7): 470-473 [Abstract] ( 1129 ) HTML (1 KB) PDF (0 KB) ( 48 )

	474	A quantitative diagnosis model for lung invasive adenocarcinoma with ground glass node
		ZHAO Liu, LIU Xin, DU Si-yao, GAO Si, ZHAO Rui-meng, ZHANG Li-na
		DOI: 10.12117/jccmi.2020.07.005
		Objective: To establish a quantitative diagnosis model for the diagnosis of lung invasive adenocarcinoma with ground glass nodule(GGN). Methods: Two hundred and seventy-eight cases of GGNs were analyzed retrospectively, including 186 cases of lung invasive adenocarcinoma(IAC) and 92 cases of non-invasive adenocarcinoma(including minor invasive adenocarcinoma MIA). The density, volume, mass, 2D long and short diameter, 3D axial diameter and standard diameter of the nodules were obtained by using the artificial intelligence recognition software. Mann Whitney U test was used to compare the parameters of IAC group and non-IAC group, and multivariate logistic analysis was used to establish quantitative parameter model and plot ROC curve. Results: There were significant differences between the IAC group and non-IAC group for all the parameters(P<0.001). After multiple logistic analysis, the density and 2D length were included to establish the quantitative diagnosis model. The ROC curve showed that the area under the curve(ROC) of the model was 0.819, which was higher than the diagnostic efficiency of each single parameter. Conclusion: The quantitative diagnosis model based on the density and 2D long diameter can effectively diagnose the invasive adenocarcinoma with ground glass density nodules.
		2020 Vol. 31 (7): 474-477 [Abstract] ( 1109 ) HTML (1 KB) PDF (0 KB) ( 51 )

	478	Value of intranodular and perinodular radiomic features to distinguish malignant from benign pulmonary nodules（≤2 cm）
		ZHANG Jing1, WU Zhi-feng2, E Lin-ning2, WANG Rong-hua2, ZHANG Na2
		DOI: 10.12117/jccmi.2020.07.006
		Objective: To investigate the value of intranodular and perinodular radiomic features to distinguish malignant from benign pulmonary nodules(≤2 cm). Methods: A retrospective analysis of 206 patients with pulmonary nodules with noncontrast CT images, including 106 malignant patients and 100 benign patients, was performed by two radiologists with 3 and 10 years of chest CT imaging experience, respectively, to evaluate without pathological results. At the same time, radiomic analysis was performed on 206 cases of nodules, and VOIs were delineated by 3D slicer, radiomic features were extracted by Analysis-Kinetics(A.K.) analysis software. The Lasso-logistic regression was performed to select features, and to establish lung nodule models, models of combining intranodular with perinodular 5 mm, 10 mm, and 15 mm tissue, respectively. ROC curve analysis and Delong test was used to compare the diagnostic efficacy among models and radiologists. Results: The AUC values of the two radiologists were 0.81 and 0.69. In the validation group, the AUC value of the lung nodule model was 0.82, and the AUC values of combining intranodular with perinodular 5 mm, 10 mm, and 15 mm tissue models were 0.88, 0.76, and 0.82. Except for the combining intranodular with perinodular 10 mm tissue model, the efficacy of the other models was higher than that of the physician group, but there was no significant difference in efficacy between the models(DeLong test, P>0.05). Conclusion: For lung nodules ≤2 cm, the models based on intranodular and perinodular radiomic features can improve the ability to distinguish benign and malignant nodules.
		2020 Vol. 31 (7): 478-481 [Abstract] ( 1128 ) HTML (1 KB) PDF (0 KB) ( 41 )

	482	Interventional therapy for pulmonary sequestration: a clinical analysis on 16 cases
		LI Lin, YANG Lian, LIU De-han, ZHANG Wei, WU Xin, ZHENG Chuan-sheng
		DOI: 10.12117/jccmi.2020.07.007
		Objective: To discuss the efficacy and safety of transarterial embolization(TAE) therapy in patients with pulmonary sequestration. Methods: Clinical data of 16 patients who suffered from pulmonary sequestration and accepted intervention therapy in our hospital from Sep 2003 to Jun 2019 were retrospectively analyzed. All patients underwent angiography and TAE with various embolic materials according to the lesion’s nature, location, extent, etc. They were followed up for 2 to 48 months(mean of 20 months) after the procedure． Results: Embolization was successfully carried out in all of them. The embolic materials included PVA and coils. After a mean follow-up of 20 months, no serious adverse effects were observed in all patients. There were no complaints of hemoptysis at the end of the follow-up period. Conclusion: Transcatheter arterial embolization is a safe and effective treatment for pulmonary sequestration.
		2020 Vol. 31 (7): 482-485 [Abstract] ( 1098 ) HTML (1 KB) PDF (0 KB) ( 41 )

	486	The value of MSCT 3D reconstruction, MRI combined with transabdominal gastric filling ultrasound for TNM staging of gastric cancer
		WANG Shan, YUN Hao, CHEN Guo
		DOI: 10.12117/jccmi.2020.07.008
		Objective: To investigate the value of multi-slice spiral CT(MSCT) 3D reconstruction, MRI combined with transabdominal gastric filling ultrasound for TNM staging of gastric cancer. Methods: From September 2016 to November 2018, 60 patients with gastric cancer who were diagnosed and treated in Wenchang People’s Hospital were selected as the study subjects. MSCT 3D reconstruction, MRI, and gastric filling ultrasound were performed before operation, TNM staging was performed according to the results of examination, and postoperative pathological staging was compared. Results: The sensitivity of MSCT 3D reconstruction, MRI, gastric filling ultrasound, and combined detection of the three for T-staging of gastric cancer was 80.00%, 85.00%, 71.67%, and 96.67%, respectively. The sensitivity of N stage was 78.33%, 76.67%, 80.00% and 93.33%, respectively, the sensitivity of M stage was 83.33%, 80.00%, 86.67% and 98.33%, respectively. The sensitivity of combined detection for T, N, and M staging of gastric cancer was significantly higher than that by single detection(P<0.05). Conclusion: MSCT 3D reconstruction, MRI combined with transabdominal gastric filling ultrasound can significantly improve the sensitivity in the diagnosis of T, N, M staging of gastric cancer, which has some value for guiding the selection of clinical treatment options and evaluation of treatment effect.
		2020 Vol. 31 (7): 486-489 [Abstract] ( 1145 ) HTML (1 KB) PDF (0 KB) ( 41 )

	490	Treatment of unresectable hepatocellular carcinoma with Huaier granule combined with TACE: prospective cohort study
		WANG Hai-rui, LIU Zhao-yu
		DOI: 10.12117/jccmi.2020.07.009
		Objective: To observe the efficacy and safety of Huaier granule combined with TACE in treatment of unresectable HCC, and to explore the factors influencing the curative effect of combined therapy. Methods: During the period from September 2014 to December 2016, a prospective cohort study was conducted in 582 patients who were continued to be enrolled. All patients meet the inclusion criteria and can not be surgically removed. In the experimental group, 342 patients were treated with Huaier granule and TACE. The HCC patients with the same baseline data were selected as the control group(240 cases), which use TACE combined with other treatment(targeted drug therapy, immunotherapy, chemoradiotherapy, etc). The primary outcome were time to progression(TTP), and the secondary outcome was adverse drug events. Finally, the factors influencing the curative effect of combined therapy were discussed. Results: Follow-up deadline was June 2019, 40 cases were lost(experimental group were 12 cases, control group 28 cases), safety assessment of 542 cases, the experimental group of 330 cases, the control group of 212 cases, 164 cases of death(experimental group of 71 cases, control group 93 cases). According to the mRECIST standard, the median tumor progression time(mTTP) of the experimental group was 582 days and control group 217 days, and the difference was statistically significant(Kaplan-Meier analysis)(P<0.05). In the experimental group, COX regression analysis showed that BCLC stage A, Child-Pugh grade A, no portal vein thrombosis with longer survival time, multivariate analysis showed that Child-Pugh grade, portal vein thrombosis or not was an independent predictive index of HCC combined therapy. During the follow-up period, the incidence of significantly related adverse reactions in the experimental group was 41 cases(11.99%), and the symptoms were digestive tract symptoms(nausea, vomiting, diarrhea, etc.), which were mild and tolerable. Thirty-six cases were relieved by themselves, and 5 cases were relieved after drug dosage reduction. Conclusion: A multicenter prospective cohort study confirmed that TACE combined with Huaier granule was effective and safe for inoperable resection of HCC. The early use of Jin Ke Huaier granule could improve the curative effect and prolong the time of tumor progression.
		2020 Vol. 31 (7): 490-494 [Abstract] ( 927 ) HTML (1 KB) PDF (0 KB) ( 51 )

	495	The value of contrast-enhanced ultrasound combined with real-time imaging virtual navigation system in the treatment of radiofrequency of difficult liver cancer
		GAO Jun-xi, HAN Wei, GU Hao, WANG Ying-xin, SONG Tao
		DOI: 10.12117/jccmi.2020.07.010
		Objective: To investigate the feasibility and safety of radiofrequency ablation for percutaneous difficult liver cancer with enhanced-contrast ultrasound combined with real-time imaging virtual navigation system. Methods: Forty-one patients with 52 lesions in the experimental group were treated with radiofrequency ablation assisted by enhanced-contrast ultrasound combined with real time virtual imaging navigation system. In the control group of 40 patients with 54 lesions were treated with radiofrequency ablation guided by enhanced CT or guided by ultrasound after laparoscopic and open the abdomen, and the differences in operative and postoperative complications, residual and recurrence rates were compared between the two groups. Results: Fifty-two lesions in the experimental group successfully completed ultrasound and CT or MRI image fusion, the image fusion success rate was 100%, and the image alignment time was 10~30 min, with an average of 15.2 min. Three of the 81 patients in the two groups developed serious complications during and after treatment, including one case of ruptured tumor hemorrhage, one case of bloody chest water, and one case of liver abscess. No serious complications occurred in the remaining cases. There was a statistically significant difference between the two groups in pain score, bleeding and fever(P<0.05). The pain score, the probability of bleeding and postoperative fever of the experimental group were all lower than those of the control group. There was no significant difference in the recurrence rate between the two groups after treatment in three and six months. Conclusion: The radiofrequency ablation of percutaneous liver cancer treated with ultrasound combined with real time imaging virtual navigation system has low incidence of residual and recurrence rate, pain and hemorrhage complications, and is feasible and safe.
		2020 Vol. 31 (7): 495-499 [Abstract] ( 1152 ) HTML (1 KB) PDF (0 KB) ( 71 )

	500	Application of ARFI in differential diagnosis of biliary atresia and evaluation of hepatic fibrosis in infants
		YU Rui-na, HUA Shao-hua, HE Xiao, LI Yan, CHEN Yang
		DOI: 10.12117/jccmi.2020.07.011
		Objective: To investigate the diagnostic value of acoustic radiation force impulse(ARFI) in biliary atresia(BA) and infantile hepatitis syndrome jaundice(IHS), and to study whether the elastic value measured was related to liver fibrosis. Methods: Forty infants with BA, 35 infants with IHS and 25 normal infants underwent two-dimensional ultrasound by Siemens Acuson S3000 color Doppler ultrasound. We used its ARFI technique to measure the liver elasticity of three groups of infants shear wave velocity(SWV) and compared between groups. The pathological stage(F0, F1, F2, F3 and F4) of liver fibrosis was confirmed by liver puncture biopsies or surgery and pathology. SWV of different hepatic fiber stages were compared. Correlation between SWV and pathological stages of liver tissue fibrosis was also analyzed. Results: The SWV value of liver in BA jaundice group was (1.98±0.31) m/s, that in IHS group was (1.13±0.21) m/s, and that in normal group was (1.10±0.24) m/s. There was significant difference among BA group, IHS group and normal group(F=10.958, P＜0.05). There was no significant difference in SWV level between IHS group and normal group(t=1.431, P=1.34). There were significant differences in liver SWV among groups F0, F1, F2, F3, F4 varying degrees of hepatic fibrosis(H=14.307, P＜0.05), there was a significant positive correlation between SWV measured values and liver fibrosis in different pathological stages(r=0.932, P＜0.05), liver fibrosis grade increased and SWV measured values increased. Conclusion: ARFI, as a noninvasive and quantitative method for evaluating the degree of liver fibrosis, provides a basis for differential diagnosis of jaundice in infants and can objectively assess the disease progression and prognosis of infants with biliary atresia.
		2020 Vol. 31 (7): 500-502 [Abstract] ( 977 ) HTML (1 KB) PDF (0 KB) ( 38 )

	503	CT and MR diagnosis of xanthogranulomatous cholecystitis
		FU De-li, XU Song-yan, LI Ming-shan
		DOI: 10.12117/jccmi.2020.07.012
		Objective: To study the CT and MR imaging diagnosis of xanthogranulomatous cholecystitis(XGC). Methods: The clinical and imaging data of 8 XGC patients confirmed by surgery and pathology in our hospital were collected, and their CT and MR manifestations and diagnostic thoughts were retrospectively studied. Results: Among the 8 cases of imaging data, the thickening of the gallbladder wall was found in 8 cases, including uniform diffuse thickening in 6 cases(75%) and localized thickening in 2 cases(25%). There were 7 cases(87.5%) of multiple intramural low-density nodules, 4 cases(50%) of biliary stones, 7 cases(87.5%) of “biscuit sign” enhancement of the gallbladder wall and complete mucosa, 7 cases(87.5%) of adjacent liver parenchyma and intestinal inflammatory infiltration, and 1 case(12.5%) of mild intrahepatic bile duct dilation. Conclusion: The CT and MR imaging features of XGC, including evenly diffuse thickening of gallbladder wall, uneven and “biscuit-like” enhancement, multiple low density and long T1, long T2 signal nodules in the gallbladder wall, choledocholithiasis, without disruption of bile-duct mucosa, inflammatory infiltration of adjacent tissues and without dilation of intrahepatic bile ducts, can provide a reliable evidence for doctor before surgical treatment.
		2020 Vol. 31 (7): 503-506 [Abstract] ( 1197 ) HTML (1 KB) PDF (0 KB) ( 38 )

	507	The diagnostic value of multimodal imaging using CT, MRI and 18F-FDG PET-CT for extranodal lymphoma of the abdomen and pelvic
		ZHOU Jun-fen1, XIA Liang1, LIU Chun-bao1, YAN Wei-peng2, LU Di-yu1
		DOI: 10.12117/jccmi.2020.07.013
		Objective: To explore the multimodal imaging features of extranodal lymphoma of the abdomen and pelvic and evaluate the diagnostic value． Methods: The clinical data and imaging features of CT, MRI and PET-CT of 97 cases with extranodal lymphoma confirmed by surgery and pathology were analyzed retrospectively. Results: The locations of 97 patients with extranodal lymphoma of the abdomen and pelvic included gastrointestinal tract, liver, pancreas, spleen, kidney and adrenal gland and bladder. Non-hodgkin lymphoma(NHL) was more common than Hodgkin’s lymphoma(HD). The most common histological subtypes were large b-cell lymphoma and follicular lymphoma. T-cell lymphoma was also more common. CT examination showed homogeneous density, MRI examination appeared uniform hypo or isointensity signal. Most showed low to middle degree dynamic delayed enhanced. Extranodal lymphoma of the abdomen and pelvic usually remained intrinsic anatomic structures. The lesion uptake of 18F-FDG was significantly higher, which showed nodular or mass sample radioactive concentration． When the necrosis was found in extranodal involvements, necrosis would form a circular-like 18F-FDG uptake increased foci． Conclusion: The CT, MRI combined with 18F-FDG PET-CT imaging features of extranodal lymphoma of the abdomen and pelvic have typical characteristic. It is important to recognize the imaging appearance of extranodal lymphoma to improve diagnostic accuracy. The final diagnosis depends on the pathology.
		2020 Vol. 31 (7): 507-511 [Abstract] ( 1132 ) HTML (1 KB) PDF (0 KB) ( 48 )

	512	Quantitative analysis of different MR sequences in precise dynamic reconstruction of ToF PET/MR by integrated simultaneous acquisition
		WANG Bo1, LIU Chang-ping1, ZHAI Wei1, ZHANG Xin1, CHEN Zhong-wei2, XIN Jun1
		DOI: 10.12117/jccmi.2020.07.014
		Objective: To analyze whether different MR sequences have an effect on PET uptake by measuring the difference in SUV values of PET images after different sequences of MR pelvic reconstruction in integrated ToF PET/MR. Methods: A retrospective collection of 15 patients with uterine malignancies(including 11 cases of cervical cancer and 4 cases of endometrial cancer) was performed on PET/MR pelvic local scan. The total scan time was 20 mins. The MR scan sequences include OAX T2WI, OAX T2WI fs, SAG T1WI, SAG T2WI fs, COR T2WI, OAX fs DWI 1000, OAX T2WI map. According to the scanning time of different sequences of MR, the PET images were reconstructed in exactly same time as the MR scanning sequences, and the SUVmax, SUVmean and background SUVmax and SUVmean of the segmented PET images corresponding to the MR scanning sequences were measured. In order to avoid the influence of time duration, the PET image was reconstructed according to the shortest scanning time of the same scanning direction sequence, and the lesion SUVmax, SUVmean and background SUVmax, SUVmean values of the PET image after short-term reconstruction are recorded, and the normal scanning time corresponding to MR is recorded. The PET image SUV values were compared. Objective statistical analysis and subjective evaluation were performed on the above results. Results: The lesions and background SUVmax and SUVmean values of the segmented PET images corresponding to the MR sequence were measured after dynamic reconstruction. There was no significant difference between SUVmax and SUVmean in normal tissues P>0.05; there were significant differences between SUVmax and SUVmean in different sequences of lesions and non-synchronized whole segments(SUVmax and SUVmean, P<0.05), and at the background, there was no significant difference between all sequences and the non-synchronized whole SUVmax and SUVmean(P>0.05). There was no significant difference in SUVmax and SUVmean between the PET obtained by short-term reconstruction and the PET dynamically reconstructed by MR(P>0.05). According to the international standard principles of the five score levels, the subjective scores of the two radiologists for the diagnosis were ≥4 points. Conclusion: The SUV values at the lesion location with different sequences(including functional sequences DWI and R2WI) are not equivalent with the entire SUV values. It is more accurate to use the segmental dynamic reconstruction, and the quantitative SUV at the background position can represent the entire SUV value. On the subjective reading, the whole PET and segmented reconstructed PET images can be substituted for each other.
		2020 Vol. 31 (7): 512-516 [Abstract] ( 873 ) HTML (1 KB) PDF (0 KB) ( 38 )

	517	Clinical value of 2D and 3D ultrasound combined with MRI in the diagnosis of fetal butterfly vertebrae
		SHANG Ning, GUO Shuang-ping, SHU Shuang, YANG Chao-xiang, HUANG Han-lin
		DOI: 10.12117/jccmi.2020.07.015
		Objective: To explore the value of 2D and 3D ultrasound combined with MRI in the diagnosis of fetal butterfly vertebrae. Methods: The cases of fetal butterfly vertebrae diagnosed by 2D, 3D ultrasound and MRI were retrospectively analyzed, then the follow-up results were collected. Results: Thirty-six cases of butterfly vertebrae were diagnosed prenatally, of which 10 cases were complicated with other deformities. Compared with the results of postnatal follow-up, the diagnostic accuracy of 2D, 3D ultrasound and MRI were 69.4%, 94.4% and 78.8%, respectively. Conclusions: 2D, 3D ultrasound and MRI have their own advantages and disadvantages in the diagnosis of fetal butterfly vertebrae. The combination of these examinations can improve the diagnostic confidence of the disease. The butterfly vertebrae without other deformities and chromosome abnormalities has good prognosis.
		2020 Vol. 31 (7): 517-519 [Abstract] ( 1139 ) HTML (1 KB) PDF (0 KB) ( 43 )

	520	Application of organ modulation technique in female chest CT scan
		YIN Wei, ZHONG Zhao-hui, QIN Xiang-yu, LI Yan, ZHAO Tian-rui, WANG Zhen-chang
		DOI: 10.12117/jccmi.2020.07.016
		Objective: To investigate the effect of organ dose modulation(ODM) on reducing radiation dose of sensitive organs in chest CT. Methods: Using a prospective case-control study design, 80 cases of patients with chest CT scan in our hospital from January to August 2019 were selected. Patients were divided into group A(n=40) and group B(n=40) by random number table method. Group A was the experimental group and group B was the control group. Patients in group A were scanned by ODM technology. Patients in group B had routine CT scan, and other parameters were as same as those in group A. Four directions tube currents, volumetric CT dose index(CTDIvol), dose length product(DLP), and effective dose(ED) were recorded at breast tissue level(anterior, left, posterior, and right) in the two groups. The region of interest(ROI) was selected from the gland region and thoracic aorta region at the breast tissue center level, and objective noise(SD) and signal-to-noise ratio(SNR) were compared. Two senior radiologists were employed to evaluate the quality of breast regional plane images on a 5-point subjective scale under the pulmonary and mediastinal Windows. Results: Among the 4 directions of breast CT tissue level in the two groups, the anterior tube current in group A was significantly lower than that in group B(P<0.05). There was no significant difference in tube current in other directions(P>0.05). Comparison of SD and SNR levels in breast region images between the two groups was statistically significant(P<0.05). Comparison of SD and SNR levels in thoracic aorta region showed no statistical significance(P>0.05). By comparing the CTDIvol and dose DLP of the two groups of patients, the difference was statistically significant(P<0.05). ED of X-ray in group A was 7.9% lower than that in group B(P<0.05). There was no significant difference in the subjective scores of the images of the transverse pulmonary window and mediastinal window between the two groups(P>0.05). Conclusion: ODM technique can effectively reduce the radiation dose of breast tissue in chest CT scan, the image quality that meets the diagnostic requirements can be obtained.
		2020 Vol. 31 (7): 520-524 [Abstract] ( 1104 ) HTML (1 KB) PDF (0 KB) ( 39 )

	525	Echocardiographic diagnosis of mediastinal teratoma: report of one case
		SU Qiao-hui, XIONG Wen-ji, ZHANG Cheng-bin, LIU Hai-hui, WANG Jing, XU Hui
		DOI: 10.12117/jccmi.2020.07.017

		2020 Vol. 31 (7): 525-526 [Abstract] ( 1188 ) HTML (1 KB) PDF (0 KB) ( 57 )

	526	Gastric duplication with soft tissue mass on CT: report of one case
		CHEN Yi-fan, ZHU Yu-chun
		DOI: 10.12117/jccmi.2020.07.018

		2020 Vol. 31 (7): 526-527 [Abstract] ( 1319 ) HTML (1 KB) PDF (0 KB) ( 41 )

	528	Percutaneous transhepatic choledocholithotomy for multiple choledocholithiasis after common bile duct surgery: report of a rare case
		MA Wei-hai, WEI Si-rong, LIU Jun-wei
		DOI: 10.12117/jccmi.2020.07.019

		2020 Vol. 31 (7): 528-529 [Abstract] ( 1029 ) HTML (1 KB) PDF (0 KB) ( 45 )

	529	Imaging analysis and literature review of primary cranial lymphoma: report of one case
		OUYANG Zhi-qiang1, LI Qian2, ZHENG Qian1, SUN Xue-jin1
		DOI: 10.12117/jccmi.2020.07.020

		2020 Vol. 31 (7): 529-531 [Abstract] ( 1234 ) HTML (1 KB) PDF (0 KB) ( 47 )

	531	2D and 3D ultrasound combined diagnosis of limb body wall complex in early pregnancy: report of one case
		DAI Song, LI Xue-lei, MU Zhong-ping
		DOI: 10.12117/jccmi.2020.07.021

		2020 Vol. 31 (7): 531-532 [Abstract] ( 1127 ) HTML (1 KB) PDF (0 KB) ( 38 )

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