Clinical application of multislice spiral CT angiography in lower extremity arterial diseases
CHEN Xiao-rong1, ZOU Song2
1. Department of Medical Image, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China; 2. CT Room, Union Hospital, Fujian Medical University, Fuzhou 350005, China
Abstract：Objective: To evaluate the clinical application of multislice spiral CT angiography(MSCTA) in diagnosing arterial diseases of the lower limb. Materials and Methods: MSCTA was performed in 43 cases suspected of arterial diseases of the lower limb. The spiral scans cover renal artery to the artery of the lower extremity, length of scanning 1000～1200mm, slice thickness 2.5mm, pitch 1.35～1.675, slice increment 1.25mm, the volume of contrast agent 100～120ml, flow rate 3.0～3.5ml/s. The method of reconstruction images included MIP, VR and MPR. Conventional digital subtraction angiography(DSA) was performed in 7 patients within 2 weeks before and after performance of MSCTA. The data of DSA and MSCTA in 130 segments with stenosis and occlusion were calculated. The sensitivity and specificity of MSCTA were calculated using DSA as the standard. Results: Forty-three cases suspected to have arterial diseases of lower limb were demonstrated successfully with MSCTA, and the quality of reconstruction images is satisfactory. Using DSA as the standard reference, the sensitivity, specificity, positive predictive value and negative predictive value of MSCTA were 96.7%, 95.7%, 95.2%, 97.1%, respectively in diagnosing stenosis and occlusion of lower limb artery. Kappa statistical analysis was used to compare the results between MSCTA and DSA(K=0.91). Conclusion: As a non-invasive, high accurate, fast-acquisition, high space resolution, low-complication technique for vascular imaging, MSCTA has a higher sensitivity, specificity and clinical application value in diagnosing arterial diseases of the lower extremities and can replace DSA to a certain extent, MSCTA can become a primary method in diagnosing arterial diseases of the lower extremities.
2008, Vol. 19 
