Abstract:Objective: To evaluate the diagnostic value of acoustic structure quantification(ASQ) technology in normal adult liver and to analyze the factors that make the differences between the groups. Methods: Four hundred and forty-nine healthy subjects, who underwent quantitative assessment of liver tissue using the acoustic structure quantification technology, were included in the study and according to gender and age were divided into elderly group(60~80 years old), middle-aged group(40~59 years old), and youth group(20~39 years old). In each group were further divided into male and female group. ASQ quantitative parameters were analyzed, including Mode, Average, and SD. Results: There was no significant difference in Mode among the age groups(P>0.05). There were significant differences in Average and SD between female elderly group and male elderly group(all P<0.05). There were significant differences in Average and Mode between female middle-aged group and male middle-aged group(all P<0.05). There were no significant differences in Mode, Average and SD between female youth group and male youth group(all P>0.05). Conclusion: Age and gender factors play important roles in the assessment of ASQ technology.