Clinical prognostic factors in unilateral moyamoya disease
ZHANG Ya-nan, XUE Jing, GAO Pei-yi
Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics(No: BZ0133), Department of Radiology,Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
Abstract:Objective: To investigate clinical prognostic factors in unilateral moyamoya disease(MMD) and provide evidence in prognosis prediction and treatment selection. Methods: A restrospective analysis of 51 patients with unilateral MMD in Tiantan Hospital between April 2008 and December 2013 was performed. Clinical data, imaging indexes, and prognosis were analyzed. Results: Of the 41 follow-up patients, those cases with cerebral infarction(CI), transient ischemic attack(TIA) and cerebral hemorrhage showed different prognosis(χ2=11.22, P<0.05), of which the prognosis of TIA group was better than that of CI group(P<0.05). In addition, the prolonged relative mean transit time(rMTT) of posterior cerebral artery(PCA) area before operation was a better prognosis factor(P<0.05). Conclusions: The clinical classification and rMTT of PCA area are factors infecting prognosis.