Abstract：Objective: To investigate the signs of renal cell carcinoma(RCC), and improve the imaging diagnosis of renal malignant neoplasm with multi-phase dynamic enhancement CT scanning. Materials and Methods: The multi-phase contrast enhanced helical CT scan data of 72 patients with surgical-pathologically proved renal malignant neoplasm were analyzed retrospectively. Fifty-seven cases of RCC, confirmed by pathological techniques, according to WHO classification, these included 38 clear cell carcinomas, 10 papillary, 8 chromophobe and 1 spindle cell RCC, were analyzed. Enhancement degrees and patterns in unenhanced, corticomedullary, nephrographic phase and excretory phase were compared. Results: CT attenuation on unenhanced scan was not statistically different. CT attenuation of clear cell carcinoma was higher than that of papillary and chromophobe RCC in corticomedullary, nephrographic and excretory phase(P value is 0.01, 0.01 and 0.03 respectively), while that of papillary and chromophobe RCC was not statistically different in all three phases. Homogeneous and heterogeneous enhancement was most commonly seen in chromophobe RCC and clear cell carcinoma. Conclusion: Dynamic enhanced CT scan was effective for differentiating clear cell carcinoma from non-clear cell carcinoma, and was useful in differentiating RCC. It could be used in formulating therapeutic plan preoperatively.
2009, Vol. 20 
