Evaluation of the correlation between BMI of healthy people and pancreatic fat quantification by IDEAL-IQ
ZHANG Qin-he1, LIU Ai-lian1, GUO Wei-ya1, TIAN Shi-feng1,#br#
LI Ye1, ZHAO Ying1, SONG Qing-wei1, XIE Li-zhi2
1. Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116011, China;
2. GE Healthcare, MR Research China, Beijing 100176, Chin
Abstract:Objective: To detect the correlation between BMI of normal healthy people and pancreatic fat quantification by using IDEAL-IQ. Materials and Methods: Thirty-two participants undergoing upper abdomen 1.5T MRI(GE 1.5T Signa HDXT, America) with IDEAL-IQ sequence, were included in this study. Participants were divided into two groups by BMI.Group A(BMI 20.4~23.5 kg/m2) are individuals of normal weight. Group B(BMI 24.0~29.6 kg/m2) are overweighted individuals. Images were uploaded to the ADW4.6 workstation and measured by the software. Three ROIs were placed at the same level in the pancreas uncinate process, head, body and tail, respectively, and the final value of pancreatic fat quantification was the average. The images were double-blindly measured by two radiologists with diagnostic experiences of 3 years and 5 years, respectively. The data were analyzed by SPSS 19.0. Results: Neither age nor gender showed statistical significance between the two groups(P>0.05). The inter-observer agreements were high. The comparison of the average pancreatic fat fraction as well as fat fraction of the pancreatic uncinate process, head and neck, body and tail between the two groups were statistically significant(P<0.05). The fat fraction of uncinate process of the pancreas was weakly correlated with BMI(r=0.396, P<0.01), and the association between the fat fraction of pancreatic head and neck, body and tail and BMI was moderate(r=0.468, 0.641 and 0.648, P<0.01, respectively). No statistical significance was found among the fat fraction of the varied pancreatic locations in the group A(P>0.05), but there was statistical significance in group B(P<0.05). The fat fraction of the body and tail was greater than that of the uncinate process and head and neck(P<0.05). Conclusion: IDEAL-IQ is a convenient and non-invasive method for quantification of pancreatic fat, which has good reproducibility and reliable results. It was found that there were significant differences in fat content of the pancreas between normally weighted and overweighted individuals. For the overweighted, the body and tail are the sensitive sites of fat infiltration in the pancreas.
张钦和1,刘爱连1,郭维亚1,田士峰1,李 烨1,赵 莹1,宋清伟1,解立志2. IDEAL-IQ评估健康人BMI与胰腺脂肪定量相关性研究[J]. 中国临床医学影像杂志, 2018, 29(7): 486-490.
ZHANG Qin-he1, LIU Ai-lian1, GUO Wei-ya1, TIAN Shi-feng1,. Evaluation of the correlation between BMI of healthy people and pancreatic fat quantification by IDEAL-IQ. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(7): 486-490.
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