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期刊信息
创刊日期:1990年
主管单位:中国人民共和国卫生部
主办单位:中国医学影像技术研究会
中国医科大学
承办单位:中国医科大学附属盛京医院
辽宁省医学影像学会
编辑出版:《中国临床医学影像杂志》
编辑部
刊 期:月刊
2018 Vol. 29, No. 8
Published: 2018-08-20
533
Current situation and challenge of magnetic resonance brain functional imaging
YU Chun-shui
DOI: DOI:10.12117/jccmi.2018.08.001
2018 Vol. 29 (8): 533-533 [
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859
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Recommendations for diagnosis and treatment of subjective cognitive decline due to preclinical Alzheimer disease in China
HAN Ying
DOI: DOI:10.12117/jccmi.2018.08.002
At present, China is the country with the largest number of people with Alzheimer disease(AD) over the world. This has posed a major burden to the health of the elderly people and the sustainable development of economy in China. There are yet no medication that can prevent the progression of AD. Given the current circumstances, the greatest possibility of combating AD should start even before the disease begins to manifest. Subjective cognitive decline(SCD), a high-risk group of AD, has been identified as the most important target persons for prevention. The National Clinical Research Center for Geriatric Disorders of Xuanwu Hospital convened a workgroup to develop recommendations for diagnosis and treatment of SCD as a part of the plan of “healthy China 2030”, a national health strategy proposed by the Chinese government in 2016, to advance early diagnosis and treatment technology for major chronic diseases as clinical practice. These recommendations include the concept of defining SCD, epidemiology, neuropsychological examinations, neuroimaging and non-pharmalogical interventions of SCD in oder to improve the understanding of AD among medical staff, and ultimately achieve the final goal of “The End of Alzheimer’s”.
2018 Vol. 29 (8): 534-538 [
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755
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539
Resting-state functional magnetic resonance imaging study of dorsal attention network in neuromyelitis optica
GUO Xi, ZHANG Xue, ZHANG Ning-nan-nan, YU Chun-shui
DOI: DOI:10.12117/jccmi.2018.08.003
Objective: To explore attention deficiency and resting-state functional connectivity strength(FCS) changes in the dorsal attention network(DAN) of neuromyelitis optica(NMO) patients. Methods: A total of 43 NMO patients and 44 age-, sex- and education-matched healthy controls were enrolled in our study. Attentional function was assessed by the symbol-digit modalities test(SDMT) and resting-state functional magnetic resonance imaging(fMRI) data were also acquired for each subject. Seed-based and conjunction analyses were used to extract the DAN. FCS maps of DAN were obtained for each subject and were then compared between the two groups using a two-sample t test. Multiple comparisons were corrected by a voxel-wise false discovery rate(FDR) method with a threshold of P<0.05. Results: NMO patients performed significantly worse on SDMT relative to healthy controls, suggesting the attention disturbance in NMO. FCS changes were also found in DAN of NMO, including decrease in bilateral postcentral gyrus, and an increase in the left superior parietal lobule and the left superior frontal gyrus. Conclusion: Altered FCS was found in DAN of NMO patients, which may be part of the neural foundation of attention deficiency in NMO.
2018 Vol. 29 (8): 539-542 [
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699
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543
Study of relationship between Tau protein changes and glutamate expression in basal ganglia after hypoxic-ischemic reperfusion injury in piglets
ZHENG Yang, WANG Xiao-ming
DOI: DOI:10.12117/jccmi.2018.08.004
Objective: To investigate the Tau protein expression and glutamate(Glu) characteristics in basal ganglia following hypoxic-ischemic(HI) reperfusion brain injury in a piglet model, further defined the Tau protein and Glu in the role of HI brain injury mechanism. Methods: A total of 45 healthy piglets(3~5 days old, 1.0~1.5 kg) were divided into control(n=9) and hypoxic-ischemic(HI) model groups(n=36). The HI model group was further divided into six groups according to 1H-magnetic resonance spectroscopy(1H-MRS) scan times after HI(0~2 h, 2~6 h, 6~12 h, 12~24 h, 24~48 h and 48~72 h). Measure Tau protein and Glu at different time points after HI in basal ganglia and the correlation of Tau protein and Glu, P<0.05 considered statistically significant, the decimal to 2 digits. Results: The results of 1H-MRS showed that after HI, the Tau protein content increased first, then decreased, and reached the highest point in 24~48 h, which was statistically different from the control group. Glu appears to rise first, then decreases, then rises again, showing a “bimodal” change, which peaks at 6~12 h and 24~48 h. Tau protein and Glu were positively correlated, correlation coefficient r=0.76(P<0.05). Conclusions: These results indicate that after HI, Tau protein and Glu work together on the neural networks and neurons and glial cells in the brain.
2018 Vol. 29 (8): 543-547 [
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669
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The value of ADC and DCE-MRI in differentially diagnosing of primary central nervous system lymphoma and demyelinating pseudotumor
CHEN Chen, REN Cui-ping, ZHAO Rui-chen, CHENG Jing-liang, WEN Bao-hong
DOI: DOI:10.12117/jccmi.2018.08.005
Objective: To assess the value of ADC and DCE-MRI in differentially diagnosing of primary central nervous system lymphoma and demyelinating pseudotumor. Methods: A total of 35 cases of PCNSL and 11 cases of the DPT confirmed by pathology were analyzed retrospectively. All of patients underwent MR scans which were obtained ADC and DCE-MRI data. Age, gender, ADC, TIC, SImax, Tmax, and MCER were measured and compared between PCNSL and DPT. The diagnostic efficacy of ADC and DCE-MRI were calculated. Two independent samples t tests, t’ test, chi-square test and Wilcoxon rank sum test were used to do statistically. Results: The ADC value((0.75±0.22)×10-3 mm2/s), MCER((115.74±7.71)%) of 35 cases of PCNSL were statistically different from 11 cases of the DPT((1.25±0.05)×10-3 mm2/s, (32.57±3.81)%). The cut-off value of ADC and MCER were respectively 1.03×10×10-3 mm2/s and 226.7% in differential diagnosis of PCNSL and DPT. There were 3 type Ⅰ TICs, 10 type Ⅱ TICs, 22 type Ⅲ TICs in 35 cases of PCNSL. There were 2 type Ⅰ TICs, 2 type Ⅱ TICs, 7 type Ⅲ TICs in 11 cases of the DPT. The age, gender, SImax, Tmax and EER were not statistically different between the two tumors(P>0.05). Conclusion: The ADC value of PCNSL is less than DPT’s; MCER of PCNSL is greater than DPT’s, and MCER is more valuable than ADC, and these parameters can help diagnosis.
2018 Vol. 29 (8): 548-551 [
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552
A study of altered resting-state functional connectivity strength in depressed schizophrenia
GUO Li-ning1, ZHUO Chuan-jun2, QIN Wen1, YU Chun-shui1
DOI: DOI:10.12117/jccmi.2018.08.006
Objective: To investigate functional connectivity strength(FCS) changes underlying depressive symptoms in patients with schizophrenia(SZ) and to analyze correlation depressive symptoms with FCS. Methods: Ninety-one SZ patients and 89 healthy controls(HC) were recruited to undergo a resting-state functional magnetic resonance imaging. The positive and negative symptom scale(PANSS) general psychopathology scale item 6(G6) was used to assess the severity of depressive symptoms in SZ. Patients were defined as depressed with scores of PANSS-G6>1, otherwise they were categorized into the non-depressed group(NDSZ). The correlation between FCS and depression severity was tested using multiple regression analysis in SZ. The FCS maps correlated with the depression symptoms were compared with one-way ANOVA among the three groups. Results: Depressive scores were strongly correlated with FCS values in the bilateral superior temporal gyrus(STG) in SZ patients. The FCS values in the bilateral STG were significantly increased in DSZ compared to NDSZ and HC. Conclusion: Schizophrenia patients with depressive symptoms have stronger FCS in the bilateral STG, which may be a possible neural mechanism of the depressive symptoms in these patients.
2018 Vol. 29 (8): 552-555 [
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676
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556
The defects of executive function in attentional deficit and hyperaction disorder: a study of Stroop effects by fMRI
LIU Jia-cheng1, CHU Xing2, XING Jiong2
DOI: DOI:10.12117/jccmi.2018.08.007
Objective: The study investigated the defects of executive function in attention deficit and hyperaction disorder(ADHD) children when they were performing Stroop color-word tasks, by functional magnetic resonance imaging(fMRI). Methods: Thirteen ADHDs and thirteen healthy controls were enrolled. The behavioral data and functional magnetic resonance images were required when the participants were performing a series of Stroop color-word tasks, in which he high conflict, low adjusted conditions and high adjusted, low conflict conditions were created by setting the ratio of congruent and incongruent trials in a block. The voxel-wise t-tests were applied to analyze the group differences of tasks, and quantified the brain response related to response time to analyze the efficiency in execution, to analyze the defects of executive function in ADHD. Results: The behavioral data showed that the adjustment, and congruence effects were significant(P<0.000 1), except the group effects(P>0.05). However, the interaction between group, adjustment and congruence were significant(P<0.02, P<0.000 1, P<0.001). The image analyses detected a cluster of right lateral prefrontal cortex(-36, 42, 33) and a cluster of anterior cingulate cortex(0, 52, 9) with lower efficiency in ADHD patients than that in healthy controls during incongruent tasks in high adjustment and conflict conditions, respectively. Conclusion: The results agree that the ADHD may arouse regions or higher activation or decrease them. The areas of lateral prefrontal cortex and anterior cingulate cortex to perform executive tasks, due to the lower efficiency in the brain areas including anterior cingulate cortex and lateral prefrontal cortex, which are related to conflict response and executive control.
2018 Vol. 29 (8): 556-559 [
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608
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560
Aberrant functional connectivity of executive control network and frontoparietal network in type 2 diabetes patients
YU Miao1, QI Na2, CUI Ying3, LIU Jia-cheng3, TENG Gao-jun3
DOI: DOI:10.12117/jccmi.2018.08.008
Objective: To investigate the integrity of executive control network(ECN), frontoparietal network(FPN) in type 2 diabetic patients by using independent component analysis(ICA), and to explore the relationship between network abnormalities, neurocognitive performance and glycaemic indices. Methods: Multidimensional cognitive function tests and rs-fMRI scans were performed in 23 T2DM patients and 25 healthy controls. Statistical analysis was conducted using REST-statistical analysis and the SPSS software. Results: Patients performed significantly worse on the MoCA, TMT-B, CFT, CFT-delayed recall and DST tests, which mainly involved cognitive domains of executive function, processing speed and spatial episodic memory. Compared with the healthy controls, patients showed decreased FC in the left parietal lobe, cingulate gyrus, right frontal lobe of ECN; increased FC in the right inferior frontal gyrus and middle frontal gyrus, decreased FC in the right postcentral gyrus of r-FPN; decreased FC in the left parietal lobe of l-FPN. Correlation analysis showed decreased connectivity in the right frontal lobe was significantly correlated with the insulin resistance level(P=0.046, r=-0.420). FC strength in the ECN and FPN was negative correlated with the neurocognitive performance. Conclusion: T2DM group manifests cognitive impairments of executive function, processing speed and spatial episodic memory and have a slective defects of ECN, FPN on right and FPN on left. The disrupted pattern of resting-state ECN was associated with IR in T2DM patients.
2018 Vol. 29 (8): 560-563 [
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Realtime shear wave elastography diagnosis value in parotid gland of primary Sjogren’s syndrome
LIU Fang, REN Wei-dong
DOI: DOI:10.12117/jccmi.2018.08.009
Objective: To study the Young’s modulus of parotid gland with primary Sjogren’s syndrome(pSS) by real-time shear wave elastography(SWE) and to explore its value in the diagnosis of parotid gland with pSS. Methods: Thirty-five patients with pSS and 35 healthy volunteers were enrolled in this study. The bilateral parotid gland were examined by SWE, and the Young’s modulus was obtained. The differences in Young’s modulus between the left and right sides of the parotid gland and between the pSS group and the non-pSS group were analyzed. Results: The Young’s modulus between two sides of parotid glands in pSS group or non-pSS group showed no significant differences(P>0.05). The difference of Young’s modulus between the two groups was statistically significant(P<0.05). Conclusion: SWE can be applied to evaluate parotid gland status with pSS.
2018 Vol. 29 (8): 564-567 [
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802
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568
Imaging manifestations of parathyroid carcinoma(6 cases and literature review)
SA Ri, GUAN Feng, DAI Yu-yin, LIN Cheng-he
DOI: DOI:10.12117/jccmi.2018.08.010
Objective: To study the imaging manifestations of parathyroid carcinoma. Methods: Ultrasonography, 99mTc-MIBI SPECT/CT(or SPECT), MRI findings and 18F-FDG PET/CT of 6 patients with parathyroid carcinoma confirmed pathologically were analyzed retrospectively, and reviewing relevant literatures. Results: Ultrasonography findings: The average maximum diameter of 6 lesions was 27.7 mm; 6 cases manifested hypoechonic, 2 of which had mirocalcifications; 3 cases showed sharp in grey scale while 3 cases presented blurred nodular margin; 4 cases had a little blood flow while 2 cases with rich blood flow. 99mTc-MIBI SPECT/CT(or SPECT) findings: 3 cases were positive and 3 cases were negative; On CT imaging, 2 cases contained microcalcifications. On MRI, 1 case showed slight low signals on T1WI and slight hyperintensity signals on T2WI, and hyperintensity signal on T1-weighted sequence. One case of postoperative 18F-FDG PET/CT found intensely high FDG uptake in multiple bones(range of SUVmax: 2.5~8.8) with osteolytic destruction and soft tissue mass. Conclusion: The imaging findings of parathyroid carcinomas have certain features. Heterogeneous intensity, microcalcifications, blurred nodular marginare helpful for diagnosis of parathyroid carcinoma. MRI can clearly manifest the relationship between adjacent tissues. 18F-FDG PET/CT is contributed to restaging, evaluation of postsurgery and follow-up of parathyroid carcinoma.
2018 Vol. 29 (8): 568-570 [
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881
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571
Diagnosis of BI-RADS 4 lesions by using the breast ultrasound types combined with ultrasound elastography
WANG Bo-juan, YANG Xiao-huan, WANG Xing-hua
DOI: DOI:10.12117/jccmi.2018.08.011
Objective: To investigate the value of breast imaging reporting and data system(BI-RADS) combined with the breast ultrasound types together with ultrasound elastography(UE) in the diagnosis of BI-RADS 4 breast lesions. Methods: Eighty-six patients with 103 breast lesions were analyzed and classified by BI-RADS for BI-RADS 4, to correct classification based on the breast ultrasound types and the score of UE. Then draw ROC curve to compare the diagnostic efficiency in breast lesions by using BI-RADS and using BI-RADS combined with the breast ultrasound types and UE. Results: Of 103 lesions, 66 lesions were benign and 37 lesions were malignant. The sensitivity of BI-RADS and BI-RADS+the breast ultrasound types+UE in the diagnosis of breast cancer was 75.7% and 91.9%. The specificity of them was 62.1% and 90.9%. The accuracy of them was 67.0% and 91.3%. The positive predictive value of them was 52.8% and 85.0%. The negative predictive value of them was 82.0% and 95.2%. AUC of them was 0.689 and 0.914. In the diagnosis of breast cancer, the specificity and accuracy of BI-RADS+the breast ultrasound types+UE were significantly higher than those of BI-RADS classification(P<0.001, P=0.028 7). Conclusions: The methods of BI-RADS+the breast ultrasound types+UE can significantly improve the value of ultrasound in the diagnosis of BI-RADS 4 breast lesions.
2018 Vol. 29 (8): 571-574 [
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575
The prediction value of microvascular invasion of hepatocellular carcinoma with CT and MR imaging features
HU Na, YANG Guo-qing, FU Quan-shui
DOI: DOI:10.12117/jccmi.2018.08.012
Objective: To discuss the correlation between various imaging features and microvascular invasion(MVI) in hepatocellular carcinoma(HCC) by using CT and MR image. Methods: Sixty-eight HCC cases confirmed by pathology underwent CT and MR examinations. Two radiologists independently reviewed radiologic images to evaluate the following features for MVI: maximum diameter, tumor margins, two-trait predictor of venous invasion(TTPVI), portal vein tumor thrombosis(PVTT) and apparent diffusion coefficient(ADC). The correlation was analyzed for prediction of MVI based on imaging features of CT and MR. The receiver operator characteristics(ROC) curve was carried out to compare the diagnostic performance for non-smooth tumor margins, TTPVI and PVTT. Results: There were excellent agreement value of the two observes(all K value>0.8). Nonsmooth tumor margins, TTPVI and PVTT were all significantly related with MVI(P<0.001); The average ADC value of MVI group was significantly higher the non-MVI group(P<0.001); The area under ROC(AUROC) of nonsmooth margins and TTPVI were both significant higher than that of PVTT(P<0.001, respectively) according to observe 1 and 2. Conclusion: Nonsmooth tumor margins, TTPVI, PVTT and ADC value are high accuracy in the prediction of MVI in HCC.
2018 Vol. 29 (8): 575-579 [
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903
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580
The value of magnetic resonance imaging in the diagnosis of female reproductive system malformation
HU Yu-fang, LIU Guang-jun, YANG Xin-guan
DOI: DOI:10.12117/jccmi.2018.08.013
Objective: To explore the application value of MRI in the diagnosis of the deformity of female reproductive system. Methods: The clinical and MRI data of 37 cases of the deformity of female reproductive system were analyzed retrospectively to explore the reasonable use of multiple scan sequences and orientation to accurately show the deformity of female reproductive system. Results: Both T2WI and T2WI-FS were the best sequences to show the deformity of female reproductive system. Combined with individualized scan orientation, various deformities of female reproductive system could be displayed clearly and intuitively. Among the 37 cases of deformities, 27 cases had uterine malformations and 10 cases had genital malformations, and the mediastinal uterine malformations were the most common, which accounted for 35.1%(13/37). There were uterine malformations combined with other lesions in 6 cases. Conclusion: According to the specific types of reproductive system deformity, it is of great significance to use the individualized scanning program for the display and diagnosis of the deformity of female reproductive system.
2018 Vol. 29 (8): 580-583 [
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901
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584
Diagnostic value of pain cause after hip prosthesis replacement by using SPECT/CT
ZHANG Bin-qing, SONG Qing-feng, GUO Hui-li
DOI: DOI:10.12117/jccmi.2018.08.014
Objective: To evaluate the diagnostic value of SPECT/CT at pain cause after hip prosthesis replacement. Methods: From Oct. 2009 to Dec. 2016, 230 hips prosthesis replacement(185 patients) with unknown pain were included in this study. CT and DR failed to find the cause of pain, then SPECT/CT imaging were carried out. The final diagnoses were made according to surgery, imaging results, or treatment outcome. All patients were followed up at least 6 months. Diagnostic efficiency of SPECT/CT was calculated. Results: One huandred and fifty-six hip joints had positive findings by SPECT/CT imaging, including 123 hip joints aseptic loosening(71 hip joints prosthesis handle loosening, 34 hip joints acetabular component loosening, 18 hip joints both loosening), 25 hip joints infection, 8 hip joints femoral stress fracture. SPECT/CT shows negative 74 hip joints(5 hip joints false negative, 69 hip joints non prosthesis or bone-derived pain). For pain cause due to prosthesis or bone-derived after hip prosthesis replacement, the diagnosis of the coincidence rate was 96.89%(156/161) by SPECT/CT. Conclusion: Once DR and CT imaging failed to diagnose the cause of pain after hip prosthesis replacement, SPECT/CT imaging may provide valuable reference information for clinical.
2018 Vol. 29 (8): 584-586 [
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DOI:10.12117/jccmi.2018.08.015
WU Quan-yang, ZHENG Rui-bin, LI Song-bai
CT perfusion(CTP) imaging after computer post-processing can show morphological changes and help us analyze functional changes. It brings a new way for the diagnosis of subarachnoid hemorrhage(SAH). CTP imaging with the help of the specific changes of different parameters have a positive effect on the diagnosis of CVS, the prediction of DCI, efficacy monitoring and clinical treatment decisions.
2018 Vol. 29 (8): 587-589 [
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787
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590
Difference diagnosis values of ultrasound in thyroid follicular carcinoma and follicular adenoma
QIN Ye-zhi, HUANG Wei-jun, LI Feng, CHEN Jiong-yuan, HE Yan-ping
DOI: DOI:10.12117/jccmi.2018.08.016
2018 Vol. 29 (8): 590-592 [
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897
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592
Pathological and ultrasonographic characteristics of Hashimoto’s thyroiditis with papillary
LV Yan-fen, LU Yong-ping, XU Fei, SUN Yue
DOI: DOI:10.12117/jccmi.2018.08.017
2018 Vol. 29 (8): 592-594 [
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824
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594
Clinical observation: the treatment of stent with particle 125I in advanced esophageal cancer by using DSA guided
YAN Tang-zhong, HOU Lu-qiang, CHI Qiang, LIU Jun-wei, WEI Si-rong, MA Wei-hai
DOI: DOI:10.12117/jccmi.2018.08.018
2018 Vol. 29 (8): 594-596 [
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529
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597
CT image analysis and review of gastric schwannoma
MO Yong-kang, XIE Lei, HUANG Jin-zhuang, LE Hong-bo, LIN Zhi-rong, MA Shu-hua
DOI: DOI:10.12117/jccmi.2018.08.019
2018 Vol. 29 (8): 597-599 [
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901
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599
Analysis of CT features and clinicopathological features of renal clear cell sarcoma in children
XIAO Wei-qiang, LIU Hong-sheng, HUANG Li
DOI: DOI:10.12117/jccmi.2018.08.020
2018 Vol. 29 (8): 599-601 [
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735
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602
Hemangioblastoma of lateral ventricle triangle area: report of one case
HAN Zhang-qiang, ZHU Yan-yan, HUANG Yan-ling
DOI: DOI:10.12117/jccmi.2018.08.021
2018 Vol. 29 (8): 602-603 [
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Ultrasound analysis of capillary hemangiomas and angiosarcomas coexist in breast: report of one case
QI Ji, ZHANG Zhen, LI Xiang
DOI: DOI:10.12117/jccmi.2018.08.022
2018 Vol. 29 (8): 603-604 [
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800
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604
Breast cyst misdiagnosed as breast carcinoma by X-ray and ultrasonography: report of one case
LI Fang, XU Mao-lin, LIU Yu-lin, HUANG Jian-guo, ZENG Shu-e, TANG Hao
DOI: DOI:10.12117/jccmi.2018.08.023
2018 Vol. 29 (8): 604-606 [
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607
Teratoid Wilms’ tumor in chindren: report of one case
YAN Zhe, LI Xin, ZHAO Bin, WANG Chun-xiang
DOI: DOI:10.12117/jccmi.2018.08.025
2018 Vol. 29 (8): 607-608 [
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